Protein Alignment ncd and klp-17

DIOPT Version :9

• Sequence 1: NP_001287592.1
• Gene: ncd / 43517
• FlyBaseID: FBgn0002924
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_496446.3
• Gene: klp-17 / 174750
• WormBaseID: WBGene00002227
• Length: 471
• Species: Caenorhabditis elegans
• Alignment Length: 492
• Identity: 172/492 - (34%)
• Similarity: 275/492 - (55%)
• Gaps: 60/492 - (12%)

  Fly   200 HDLLEKHKVLKTKYEKQTEDMGELESMPQQLE--ETQNKLIETESSLKNTQS--DNECLQRQVKQ 260
            :||  ||::  .:.|::|..:.:||:   ||.  :.|||::..||:|..:.|  |...::.|
 Worm    16 NDL--KHQI--AQLERKTATIPKLEN---QLHKAKNQNKVLRRESALFPSASCADVSRVEDQ--- 70

  Fly   261 HTAKIETITSTLGRTKEELSELQAIHEKVKTEHAALSTEVVHLRQRTEELLRCNEQQAAELETCK 325
               |::|:.:.|...|.:|.:|:..:::...|:..|..|...|::...:|:.|.:.|.||    |
 Worm    71 ---KVKTLRNELADLKLKLRQLEDDNKEKDMENDRLIQENRTLKREKLKLINCFKTQMAE----K 128

  Fly   326 EQLFQSNMERKELHNTVMDLRGNIRVFCRIRPPLESEENRMCCTWTYHDESTVELQSIDAQAKSK 390
            :.:.      :||::.|:||||.|||..|:|    ..|......::...::.|:||....|:.:
 Worm   129 DAII------RELNDEVVDLRGQIRVAIRVR----DFERDGSSNFSIISQNEVQLQQTTGQSNT- 182

  Fly   391 MGQQIFSFDQVFHPLSSQSDIFEMVSPLIQSALDGYNICIFAYGQTGSGKTYTMDG--VPESVGV 453
                 :||:.||.|.::||.:|..:..||..||.|.|:|:.|||.||||||:||.|  ..:|.||
 Worm   183 -----YSFEHVFFPPTAQSGVFGEIKELIMCALHGKNVCLIAYGPTGSGKTFTMRGEDSADSEGV 242

  Fly   454 IPRTVDLLFD-SIRGYRNLGWEYEIKATFLEIYNEVLYDLLSNEQK-DMEIRMAKNN---KNDIY 513
            |||.:..:.: |.|....:||.|:.:|:|:|:|||.:||||..:|| :::|..:|.|   ...|.
 Worm   243 IPRAIRFMLEQSKRDLAMIGWNYKFQASFIEVYNEEVYDLLDGKQKLEVKINGSKTNVVGLKKIE 307

  Fly   514 VSNITEETVLDPNHLRHLMHTAKMNRATASTAGNERSSRSHAVTKLELIGRHAEKQEISVGSINL 578
            :.||::..|        :::.|...|:.||||.||.||||||:.::.:.|::|..:.:.. .:||
 Worm   308 IGNISDVDV--------ILNLADSQRSVASTASNEHSSRSHAIFQIFVDGQNASGEMVQC-CLNL 363

  Fly   579 VDLAGSESPK-TSTR---MTETKNINRSLSELTNVILALLQKQDHIPYRNSKLTHLLMPSLG-GN 638
            |||||||..| |..|   .||..|||:|||.|...|.|.:.|..|:|||:||||.:|...|| |:
 Worm   364 VDLAGSERAKETQARGKQFTELTNINQSLSTLKKCIRAQMTKMSHVPYRDSKLTMVLREYLGAGS 428

  Fly   639 SKTLMFINVSPFQDCFQESVKSLRFAASVNSCKMTKA 675
            |||:...:.:| :| ..|:.::|.|.:.:.|..:.||
 Worm   429 SKTMFIAHANP-RD-VAETKRTLEFTSELRSTNLGKA 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ncd	NP_001287592.1	KISc_C_terminal	346..672	CDD:276817	130/337 (39%)
		KISc	348..678	CDD:214526	130/340 (38%)
klp-17	NP_496446.3	Mplasa_alph_rch	<11..146	CDD:275316	42/152 (28%)
		PRK03992	70..>116	CDD:179699	11/51 (22%)
		KISc	145..464	CDD:214526	130/340 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0239
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	236	1.000	Inparanoid score	I2140
Isobase	1	0.950	-	0	Normalized mean entropy	S1681
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D181609at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101893
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1242
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.720