Protein Alignment ncd and klp-16

DIOPT Version :9

• Sequence 1: NP_001287592.1
• Gene: ncd / 43517
• FlyBaseID: FBgn0002924
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_492527.1
• Gene: klp-16 / 172784
• WormBaseID: WBGene00002226
• Length: 587
• Species: Caenorhabditis elegans
• Alignment Length: 702
• Identity: 206/702 - (29%)
• Similarity: 303/702 - (43%)
• Gaps: 153/702 - (21%)

  Fly     6 PKPSGLKKPQMPIKTVLPTDRIRAGLGGG-AAGAGAFNVNANQTYCGNLLPPLSRDLNNLPQVLE 69
            ||.:..:....|||...|....|....|| ..||.|..            ||     :.||....
 Worm    19 PKATRGRAAAPPIKEADPATIPRQSAPGGITIGAAACR------------PP-----SRLPGATI 66

  Fly    70 RRGGGARAASPEPMKLGHRAKLRRSRSACDINELRGNKRTAAAPSLPSIPSKVSRLGGALTVSSQ 134
            ...|  ||:.||...:...:....||                 |:|.|..|:.:.|..|.|....
 Worm    67 SATG--RASLPERSAMAKTSTSSHSR-----------------PALQSTASRNTTLTAASTSRQL 112

  Fly   135 RLVRPAAPSS--ITATAVKRPPVTRPAPRAAGGAAAKKPAGTGAAASSGAAAAAPKRIAPYDFKA 197
            |..||..||:  .|||...:|.|.|..|      .|:||             ..|.::.
 Worm   113 RTGRPPPPSTQRSTATFSLKPSVARARP------VAQKP-------------ILPSKVT------ 152

  Fly   198 RFHDLLEKHKVLKTKYEKQTEDMGE-----LESMPQQLEETQNKLIETESSLKNTQSDNECLQRQ 257
                |||:......:...:..|..|     ::.:..:||....|||..:
 Worm   153 ----LLEERNAQLEREMAEATDFAEHQKSKIQFLDGKLEGADRKLISLQ---------------- 197

  Fly   258 VKQHTAKIETITSTLGRTKEELSELQAIHEKVKTEHAALSTEVVHLRQRTEELLRCNEQQAAELE 322
                               ::||.|:.:|                 :.:.||   |.|.:... .
 Worm   198 -------------------DQLSTLKEVH-----------------KSKMEE---CEEYRVHN-N 222

  Fly   323 TCKEQLFQSNMERKELHNTVMDLRGNIRVFCRIRPPLESEENRMCCTWTYHDESTVELQSIDA-- 385
            ..::.|.:...|.::|||.|:||||.|||..|:||.::||.:.        ..|.:|..::||
 Worm   223 DLRDLLNEKEAELRKLHNDVVDLRGQIRVAVRVRPLIKSEVDT--------SSSAIEYPAVDAIK 279

  Fly   386 -QAKSKMGQQIFSFDQVFHPLSSQSDIFEMVSPLIQSALDGYNICIFAYGQTGSGKTYTM-DGVP 448
             ...||.| .:..|:.||.|:.||.::|..|...|:|:|.|||:.:.||||||||||:|| .|..
 Worm   280 INEGSKPG-NVVKFENVFTPVFSQKEVFANVEEFIRSSLHGYNVGLIAYGQTGSGKTHTMRGGNG 343

  Fly   449 ESVGVIPRTVDLLFDSIRGYRNLGWEYEIKATFLEIYNEVLYDLLSNEQKDMEIRMAKNNKNDIY 513
            |..|:|||....||...:...:|||:::...:|||:||.|.|||||.... :::|:   |...:.
 Worm   344 EEEGIIPRAAAFLFAESKKLESLGWKFDFSLSFLEVYNNVAYDLLSGRDV-VQLRL---NDQTVS 404

  Fly   514 VSNITEETVLDPNHLRHLMHTAKMNRATASTAGNERSSRSHAVTKLELIGRHAEKQEISVG-SIN 577
            :..::|.|:.:.:.:..|:..|...|.||:|..|..|||||||...: |..|.....||.. .:.
 Worm   405 MIGLSEHTISNVSDVARLLRVADGGRKTAATKCNGSSSRSHAVYMWK-IKAHQPSTGISTTCQLK 468

  Fly   578 LVDLAGSESPKTS----TRMTETKNINRSLSELTNVILALLQKQDHIPYRNSKLTHLLMPSLG-G 637
            ||||||||..|.|    .:..|..|||:|||.|...|.....::.|:.||:||||.:||..|| |
 Worm   469 LVDLAGSERAKESGVSGDQFKEMTNINQSLSILQMCISQQRSQKGHVSYRDSKLTQVLMDCLGRG 533

  Fly   638 NSKTLMFINVSPFQDCFQESVKSLRFAASVNSCKMTKAKRNRYLNNSVANSS 689
            :|||::.:|::|..:...||.:|:.||:.:.|..:..|.:.|.|...|:..|
 Worm   534 SSKTMVVVNLNPCNEQATESKRSIEFASKMRSTHIGSAVQQRTLLGDVSQMS 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ncd	NP_001287592.1	KISc_C_terminal	346..672	CDD:276817	129/335 (39%)
		KISc	348..678	CDD:214526	128/339 (38%)
klp-16	NP_492527.1	PHA03247	<16..152	CDD:223021	46/187 (25%)
		ATG16	150..>250	CDD:370001	28/165 (17%)
		KISc	248..564	CDD:276812	126/329 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0239
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	236	1.000	Inparanoid score	I2140
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D181609at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101893
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1242
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.770