Protein Alignment ncd and klp-15

DIOPT Version :9

• Sequence 1: NP_001287592.1
• Gene: ncd / 43517
• FlyBaseID: FBgn0002924
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_491633.1
• Gene: klp-15 / 172213
• WormBaseID: WBGene00002225
• Length: 587
• Species: Caenorhabditis elegans
• Alignment Length: 691
• Identity: 205/691 - (29%)
• Similarity: 311/691 - (45%)
• Gaps: 137/691 - (19%)

  Fly    26 RIRAGLGGGAAGAGAFNVNANQTYCGNLLPPLSRDLNN--LPQVLERRGGGARAASPEPMKLGHR 88
            |.|:||.....||      ..:...|....|.:::.|:  :|          |.::|..:.:|..
 Worm     5 RRRSGLFRSTIGA------TPKITRGRAAAPSTKEANSTTIP----------RQSAPGGITIGAA 53

  Fly    89 AKLRRSRSACDINELRGN----KRTAAA---------PSLPSIPSKVSRLGGALTVSSQRLVRPA 140
            |:...||.........|.    :|:|.|         |::.|..|::|.|..|.|....|..||.
 Worm    54 ARRPPSRLPTPTTPATGRASLPERSAMAKPASCSRPIPTMQSTASRISTLTAASTFRQLRTGRPP 118

  Fly   141 APSS--ITATAVKRPPVTRPAPRAAGGAAAKKPAGTGAAASSGAAAAAPKRIAPYDFKARFHDLL 203
            .||:  .|||:..:|.|||..|      .|:||.
 Worm   119 PPSTQRSTATSSLKPSVTRARP------VAQKPI------------------------------- 146

  Fly   204 EKHKVLKTKYEKQTEDMGELESMPQQLEETQNKLIETESSLKNTQSDNECLQRQVKQHTAKIETI 268
                                  :|.::...:.|:.:.||::.......|..:.:::....|:|..
 Worm   147 ----------------------LPSKMALLEEKIAQLESAMAEATDFAEHQKSKIQILDGKLEGA 189

  Fly   269 TSTLGRTKEELSELQAIHEKVKTEHAALSTEVVHLRQRTEELLRCNEQQAAELETCKEQLFQSNM 333
            ...|...:::||.|:.:: |.|.|      |....|....:|              ::.|.:...
 Worm   190 DRKLISLQDQLSTLKEVN-KAKVE------ECEDYRVHNNDL--------------RDLLNEKEA 233

  Fly   334 ERKELHNTVMDLRGNIRVFCRIRPPLESEENRMCCTWTYHDESTVELQSIDA---QAKSKMGQQI 395
            |.::|||.|:||||.|||..|:||.::||.:.        ..|.:|..:||.   ...||.| .:
 Worm   234 ELRKLHNDVVDLRGQIRVAVRVRPLIKSEADA--------SSSAIEYPAIDTIRINEGSKPG-IV 289

  Fly   396 FSFDQVFHPLSSQSDIFEMVSPLIQSALDGYNICIFAYGQTGSGKTYTM-DGVPESVGVIPRTVD 459
            ..|::||.|:.||.::|..|...|:|:|.|||:.:.||||||||||:|| .|..|..|:|||...
 Worm   290 VKFEKVFTPVFSQKEVFANVEEFIRSSLHGYNVGLIAYGQTGSGKTHTMRGGNGEEEGIIPRAAA 354

  Fly   460 LLFDSIRGYRNLGWEYEIKATFLEIYNEVLYDLLSNEQKDMEIRMAKNNKNDIYVSNITEETVLD 524
            .||...|...:|||:::...:|||:||.|.|||||    |..:...:.|...:.:..::|.|:.:
 Worm   355 FLFAESRKLESLGWKFDFSLSFLEVYNNVAYDLLS----DRAVVQLRLNDQTVSMIGLSEHTISN 415

  Fly   525 PNHLRHLMHTAKMNRATASTAGNERSSRSHAVTKLELIGRHAEKQEISVG-SINLVDLAGSESPK 588
            .:.:..|:..|...|.||:|..||.|||||||...: |..|.....||.. .:.||||||||..|
 Worm   416 VSDVARLLRVADGGRKTAATKCNESSSRSHAVYMWK-ITAHQPSTGISTSCQLKLVDLAGSERAK 479

  Fly   589 TS----TRMTETKNINRSLSELTNVILALLQKQDHIPYRNSKLTHLLMPSLG-GNSKTLMFINVS 648
            .|    .:..|..|||:|||.|...|.....::.|:.||:||||.:||..|| |||||::.:|::
 Worm   480 ESGVSGDQFKEMTNINQSLSILQMCISQQRSQKGHVSYRDSKLTQVLMDCLGRGNSKTMVVVNLN 544

  Fly   649 PFQDCFQESVKSLRFAASVNSCKMTKAKRNRYLNNSVANSS 689
            |..:...||.:|:.||:.:.|..:..|.:.|.|...|:..|
 Worm   545 PCNEQATESKRSIEFASKMRSTNIGSAVQQRTLLGDVSQMS 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ncd	NP_001287592.1	KISc_C_terminal	346..672	CDD:276817	132/335 (39%)
		KISc	348..678	CDD:214526	131/339 (39%)
klp-15	NP_491633.1	PHA03378	<27..153	CDD:223065	37/194 (19%)
		Tropomyosin_1	<147..242	CDD:372267	22/115 (19%)
		ABC_tran_CTD	147..193	CDD:379824	7/45 (16%)
		KISc	248..564	CDD:276812	129/329 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0239
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	236	1.000	Inparanoid score	I2140
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D181609at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101893
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1242
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.770