DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ncd and AgaP_AGAP007706

DIOPT Version :9

Sequence 1:	NP_001287592.1	Gene:	ncd / 43517	FlyBaseID:	FBgn0002924	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	XP_308170.4	Gene:	AgaP_AGAP007706 / 1269528	VectorBaseID:	AGAP007706	Length:	871	Species:	Anopheles gambiae

Alignment Length:	434	Identity:	113/434 - (26%)
Similarity:	187/434 - (43%)	Gaps:	98/434 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   336 KELHNTVMDLRGN---------IRVFCRIRPPLESEENRMCCTWTYHDESTVELQSIDAQAKSKM 391
            |.|..:.:..|||         ::|:||:||| ..|.:..|...|  |..||.|...:.....|:
Mosquito    11 KVLPKSAIKSRGNSGNNLGKDPVQVYCRVRPP-PCESDLTCLRVT--DPHTVVLTPPEIAINYKI 72

  Fly   392 G---QQIFSFDQVFHPLSSQSDIFEMVS-PLIQSALDGYNICIFAYGQTGSGKTYTMDGVPESVG 452
            .   :..:.|.:||.....|.:::..|: ||::..:.|.|..:|.||.|||||||||.|..:..|
Mosquito    73 ANLKETQYIFKRVFDDAVRQHEVYVSVAQPLVEGLIRGRNGLLFTYGVTGSGKTYTMTGDLQHRG 137

  Fly   453 VIPRTVDLLFDSIRGY-----------------------------------------RNLGWE-- 474
            ::||.:|.||.:|..|                                         ::|..|
Mosquito   138 IMPRCLDALFRTIADYQAKKYTFKSDRLNGFDILTEAEVLLERQAELNAKLTKSTRKKDLDQEVA 202

  Fly   475 ------------------YEIKATFLEIYNEVLYDLL--SNEQKDMEIRMAKNN-KNDIYVSNIT 518
                              |.:...::|:||..:||||  :..||.::.:|.:.: :::::|..:|
Mosquito   203 SQVSVEPSEISGIEEDNIYAVFINYVEVYNNSVYDLLEETTVQKTLQSKMVREDAQHNMFVHGVT 267

  Fly   519 EETVLDPNHLRHLMHTAKMNRATASTAGNERSSRSHAVTKLELI-------GRHA--EKQEISVG 574
            |..|........|....:..:....|..|..|||||:|..:.|:       |.:.  ::..|:|.
Mosquito   268 EVEVKSVEEALELFQIGQKRKRMGHTILNAESSRSHSVFTIRLVQAPVDVQGENVVQDRNAITVS 332

  Fly   575 SINLVDLAGSE----SPKTSTRMTETKNINRSLSELTNVILALLQKQD-----HIPYRNSKLTHL 630
            .::||||||||    :..|..|:.|..|||.||..|...:..|.:.|.     .:|||:||:|||
Mosquito   333 QLSLVDLAGSERTNRTGNTGQRLREAGNINNSLMTLRTCLEILRENQQTCGGKKVPYRDSKITHL 397

  Fly   631 LMPSLGGNSKTLMFINVSPFQDCFQESVKSLRFAASVNSCKMTK 674
            ......|..:..|.:.|:|..:.:.|:.:.::||......::.:
Mosquito   398 FKNYFDGEGQVRMIVCVNPRAEDYDETAQVMKFAEMTQDVQIAR 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ncd	NP_001287592.1	KISc_C_terminal	346..672	CDD:276817	111/420 (26%)
ncd	NP_001287592.1	KISc	348..678	CDD:214526	109/422 (26%)
AgaP_AGAP007706	XP_308170.4	KISc_KIF23_like	31..435	CDD:276819	108/406 (27%)
		Kinesin	38..437	CDD:278646	106/401 (26%)
		Uds1	508..612	CDD:292096
		Tropomyosin_1	546..675	CDD:289488
		TMPIT	588..>661	CDD:285135
		MKLP1_Arf_bdg	720..821	CDD:293148
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910