DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ncd and LOC100490298

DIOPT Version :9

Sequence 1:	NP_001287592.1	Gene:	ncd / 43517	FlyBaseID:	FBgn0002924	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	XP_012815398.1	Gene:	LOC100490298 / 100490298	-ID:	-	Length:	764	Species:	Xenopus tropicalis

Alignment Length:	510	Identity:	178/510 - (34%)
Similarity:	257/510 - (50%)	Gaps:	50/510 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   194 DFKARF--HDLLEKHKV---LKTKYEKQTEDMGELESMPQQLEETQNKLIE----TESSLKNTQS 249
            :|:..|  .|:.|..|:   |..|.:.|..::..|:...|.|||.:.|||:    ....|...|:
Frog   264 NFEQMFLHRDIQENKKIIENLNKKLQSQDRELVNLQLKCQYLEEEKGKLIDRAENMSKKLAELQA 328

  Fly   250 DNECLQRQV----KQHTAKIETITSTLGRTKEE-LSELQAIHE--------KVKTEHA--ALSTE 299
            ::|..|::.    |..|.......:.|...||. |:.||...|        :|.|::|  .:..:
Frog   329 EHEIHQQEAARAGKSQTQSESKEKAVLPLKKEALLNILQESRELNVCNNQLRVVTKNALSEIGLQ 393

  Fly   300 VVHLRQRTEELLRCNEQQAAELETCKEQLFQSNMERKELHNTVMDLRGNIRVFCRIRPPLESEEN 364
            :.||:..||.:.|.|:    |:|..:....:..:|||.|:|.:.:||||||||||.|    .::|
Frog   394 LRHLQNTTENMNRSNK----EVEEIRALYQRECLERKMLYNQLQELRGNIRVFCRCR----RDDN 450

  Fly   365 RMCCTWTYHDESTVELQSIDAQAKSKMGQQIFSFDQVFHPLSSQSDIFEMVSPLIQSALDGYNIC 429
            :        .:....|...|....:...::.|.|||||.|..||.|:||...|:|:|.:||||:|
Frog   451 K--------GDHLEFLSGEDILINNNGNKKKFRFDQVFLPQCSQEDVFEGTLPIIKSCVDGYNVC 507

  Fly   430 IFAYGQTGSGKTYTMDGVPESVGVIPRTVDLLFDSIRGYRNLGWEYEIKATFLEIYNEVLYDLL- 493
            |.|||||||||||||.|..:..||..|:|..|....:...|:  .|..|.:.||||||.|.|||
Frog   508 ILAYGQTGSGKTYTMMGPEQKPGVNIRSVKELIRICQERENI--RYTTKISMLEIYNETLRDLLV 570

  Fly   494 SNEQKDMEIRMAKNNKNDIYVSNITEETVLDPNHLRHLMHTAKMNRATASTAGNERSSRSHAVTK 558
            .|....:|||   :....:.|..:.|..|.....:|..:...:.||..|||..|..|||||.:..
Frog   571 QNGNTQLEIR---SQGKMVTVPGLKEIEVQTEEDIRKTISLGEKNRTVASTKMNTESSRSHLMVI 632

  Fly   559 LELIGRHAEKQEISVGSINLVDLAGSE----SPKTSTRMTETKNINRSLSELTNVILALLQKQDH 619
            |.:.|..:....:|..::.|.||||||    :..|..|:.|...||:||:.|..|..||.....|
Frog   633 LHINGVDSISGVVSTATLTLCDLAGSERISKTEATGQRLMEAAAINKSLTALGQVFTALKNNSLH 697

  Fly   620 IPYRNSKLTHLLMPSLGGNSKTLMFINVSPFQDCFQESVKSLRFAASVNSCKMTK 674
            :|||||||||||.|||.|.:|..:|:|:||......|::.:|:|.:|:....:.|
Frog   698 VPYRNSKLTHLLQPSLSGQAKACVFVNISPDIKDIGETISTLQFGSSIQQIALGK 752

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ncd	NP_001287592.1	KISc_C_terminal	346..672	CDD:276817	131/330 (40%)
ncd	NP_001287592.1	KISc	348..678	CDD:214526	130/332 (39%)
LOC100490298	XP_012815398.1	SMC_prok_B	<214..>439	CDD:274008	48/178 (27%)
LOC100490298	XP_012815398.1	Motor_domain	436..750	CDD:354959	131/330 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D181609at33208
OrthoFinder	1	1.000	-	-		FOG0000325
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010