Protein Alignment CG7789 and INPP1

DIOPT Version :9

• Sequence 1: NP_651728.1
• Gene: CG7789 / 43516
• FlyBaseID: FBgn0039698
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_001122400.1
• Gene: INPP1 / 3628
• HGNCID: 6071
• Length: 399
• Species: Homo sapiens
• Alignment Length: 400
• Identity: 98/400 - (24%)
• Similarity: 154/400 - (38%)
• Gaps: 132/400 - (33%)

  Fly    13 ASSISTAKRAGGIIRDVL----KKGDLGIVDKGKN---DPQTEADRSAQRCIIASLAKKFPTVK- 69
            |::|:.|.|....:..:|    |:|     :|.|.   |.:|.||...|..|..::..|||.::
Human    15 AANIARACRQQEALFQLLIEEKKEG-----EKNKKFAVDFKTLADVLVQEVIKQNMENKFPGLEK 74

  Fly    70 -IIGEEGGSDLNVCDDWLVNELDEEFLQHSCPAE-------------------------WKDVK- 107
             |.|||.....|   ||     .|:.....|..|                         .:||.
Human    75 NIFGEESNEFTN---DW-----GEKITLRLCSTEEETAELLSKVLNGNKVASEALARVVHQDVAF 131

  Fly   108 ------------PEDFV-IWVDPLDGTAEYTQGH-------------VEHVTVLIGIAVKDAAVG 146
                        |:|.: |||||:|.|.:|.:|.             ::.||:|||  |.|...|
Human   132 TDPTLDSTEINVPQDILGIWVDPIDSTYQYIKGSADIKSNQGIFPCGLQCVTILIG--VYDIQTG 194

  Fly   147 ----GIIHQPFYQQPDGEM---GRTIWGLKGLGTG---------------------GFTAVPAPA 183
                |:|:|||..:....:   |:..|||..:||.                     |..|..:|:
Human   195 VPLMGVINQPFVSRDPNTLRWKGQCYWGLSYMGTNMHSLQLTISRRNGSETHTGNTGSEAAFSPS 259

  Fly   184 GQFIITTTRSHSNALHQQALNAFASTEVLKVGGAGFKVLQLLEGKAHAYVFATPGCKKWDTCAPE 248
            ...:|:|:...:   .:.||:......:....|||:|.|.:::|....|:|:.....|||:||..
Human   260 FSAVISTSEKET---IKAALSRVCGDRIFGAAGAGYKSLCVVQGLVDIYIFSEDTTFKWDSCAAH 321

  Fly   249 AVLEAQGG-------CL-----TNINGEHYAYNADVE-------HVNRQGVLASLGQDH-----A 289
            |:|.|.||       ||     |.::.....|:.:.|       ..|:.|::|...:..     :
Human   322 AILRAMGGGIVDLKECLERNPETGLDLPQLVYHVENEGAAGVDRWANKGGLIAYRSRKRLETFLS 386

  Fly   290 ALVEKI-PAE 298
            .||:.: |||
Human   387 LLVQNLAPAE 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7789	NP_651728.1	IPPase	12..294	CDD:238818	95/393 (24%)
INPP1	NP_001122400.1	IPPase	4..387	CDD:238818	93/389 (24%)
		Substrate binding. /evidence=ECO:0000250	155..158		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1096950at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820