DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7789 and bpnt-1

DIOPT Version :9

Sequence 1:	NP_651728.1	Gene:	CG7789 / 43516	FlyBaseID:	FBgn0039698	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_494780.1	Gene:	bpnt-1 / 173777	WormBaseID:	WBGene00044063	Length:	319	Species:	Caenorhabditis elegans

Alignment Length:	320	Identity:	144/320 - (45%)
Similarity:	190/320 - (59%)	Gaps:	39/320 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 APVIMRVMASSISTAKRAGGIIRDVLKKGDLGIVDKGKN----DPQTEADRSAQRCIIASLAKKF 65
            |..:.|::|||:..::.|||:|::|:..|||.|:||.::    ||||||||.||.||:.||.|.|
Worm     5 ASFLTRLVASSVRVSEAAGGLIKNVMAGGDLKIIDKSEHGSGYDPQTEADRRAQYCIVQSLQKHF 69

  Fly    66 PTVKIIGEEGGSDLNVCDDWLVNELDEEF------LQHSCPAEWKDVKPEDFVIWVDPLDGTAEY 124
            ..:.|||||  .|...|.     |::..|      ::.....|.|:::..|.|:||||||||:|.
Worm    70 KNINIIGEE--EDTTACP-----EIEMGFSADVLQMERLMSTELKNIQENDVVVWVDPLDGTSEV 127

  Fly   125 -------TQGHVEHVTVLIGIAVKDAAVGGIIHQPFYQQPDGEMGRTIWGLKGLGTGGFTAVPAP 182
                   ....:|.||||||||.|...|.||||||:::    ::|||:|.::|.|..|  .|||.
Worm   128 ALAVKNKNMALLEQVTVLIGIAYKGRPVAGIIHQPYHE----KLGRTVWAIQGCGVHG--VVPAT 186

  Fly   183 A-GQFIITTTRSH-----SNALHQQALNAFASTEVLKVGGAGFKVLQLLEGKAHAYVFATPGCKK 241
            . .|.|:.|||||     ||||........|.: |.||||||||||::|||.| |||||:.||||
Worm   187 GNAQKIVVTTRSHLSESVSNALEALKTRNLADS-VEKVGGAGFKVLKVLEGCA-AYVFASAGCKK 249

  Fly   242 WDTCAPEAVLEAQGGCLTNINGEHYAYNADVEHVNRQGVLASLG-QDHAALVEKIPAEVR 300
            |||||.||||.|.||.||:|:|....|...|:..|..||||:.. ..|...::.||.|::
Worm   250 WDTCAVEAVLTAAGGTLTDISGRDIRYEPGVQLNNTGGVLATASWVKHKDYIDTIPQEIK 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7789	NP_651728.1	IPPase	12..294	CDD:238818	139/305 (46%)
bpnt-1	NP_494780.1	IPPase	11..303	CDD:238818	139/306 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166134
Domainoid	1	1.000	217	1.000	Domainoid score	I1551
eggNOG	1	0.900	-	-		E1_COG1218
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4437
Inparanoid	1	1.050	229	1.000	Inparanoid score	I2209
Isobase	1	0.950	-	0	Normalized mean entropy	S2481
OMA	1	1.010	-	-		QHG55155
OrthoDB	1	1.010	-	-		D1096950at2759
OrthoFinder	1	1.000	-	-		FOG0007501
OrthoInspector	1	1.000	-	-		oto17424
orthoMCL	1	0.900	-	-		OOG6_103421
Panther	1	1.100	-	-	LDO	PTHR43028
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3949
SonicParanoid	1	1.000	-	-		X5632
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750