Protein Alignment Drice and CASP10

DIOPT Version :10

• Sequence 1: NP_524551.2
• Gene: Drice / 43514
• FlyBaseID: FBgn0019972
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_116759.2
• Gene: CASP10 / 843
• HGNCID: 1500
• Length: 522
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 102/295 - (34%)
• Similarity: 152/295 - (51%)
• Gaps: 36/295 - (12%)

  Fly    24 NDHTDALGSVGSGGAGSSGLVAGSSHPYGSGAIGQLANGYSSPSSSYRKNVAKMVTDRHAAEYNM 88
            |.|..:.|:..:.||.|  ||:       .|..|..||..:|.:|:.|           ||.|.|
Human   234 NKHAGSNGNRATNGAPS--LVS-------RGMQGASANTLNSETSTKR-----------AAVYRM 278

  Fly    89 RHKNRGMALIFNHEHFEVPTLKSRAGTNVDCENLTRVLKQLDFEVTVYKDCRYKDILRTIE-YAA 152
            ...:||:.:|.|:..|  .:||.|.||:.|.|.|:.|.:.|.|.|.::.:....::...:: ...
Human   279 NRNHRGLCVIVNNHSF--TSLKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKC 341

  Fly   153 SQNHSDSDCILVAILSHGEMGYIYAKD-TQYKLDNIWSFFTANHCPSLAGKPKLFFIQACQGDRL 216
            :..|:|.||.:..||:||..|.:|:.| ....:..|.|.|||..||.||.||||||||||||:.:
Human   342 NPAHADGDCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEI 406

  Fly   217 DGGVTMQRSQTETD-GDSSMSYKIPVHADFLIAYSTVPGFYSWRNTTRGSWFMQSLCAELAANGK 280
            ...|:::......: ..:|:...||..||||:..:||||:.|:|:...|||::||||..|    |
Human   407 QPSVSIEADALNPEQAPTSLQDSIPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHL----K 467

  Fly   281 RL-----DILTLLTFVCQRVA--VDFESCTPDTPE 308
            :|     |||::||.|...|:  ||.:......|:
Human   468 KLVPRHEDILSILTAVNDDVSRRVDKQGTKKQMPQ 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drice	NP_524551.2	CASc	86..330	CDD:214521	85/233 (36%)
CASP10	NP_116759.2	DD	18..99	CDD:472698
		DED_Caspase_10_r2	112..190	CDD:260074
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	231..269		13/43 (30%)
		CASc	276..514	CDD:214521	85/233 (36%)