Protein Alignment Drice and CASP4

DIOPT Version :9

• Sequence 1: NP_524551.2
• Gene: Drice / 43514
• FlyBaseID: FBgn0019972
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_001216.1
• Gene: CASP4 / 837
• HGNCID: 1505
• Length: 377
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 70/276 - (25%)
• Similarity: 118/276 - (42%)
• Gaps: 49/276 - (17%)

  Fly    76 KMVTDRHAAEYNMRHKNR--GMALIFNHEHFEVPTLKSRAGTNVDCENLTRVLKQLDFEVTVYKD 138
            ::..:|....|.::.:|.  .:|||..:..|:  .|..|.|.:.|...:..:|:.||:.|.|.::
Human   116 RLCKERAEEIYPIKERNNRTRLALIICNTEFD--HLPPRNGADFDITGMKELLEGLDYSVDVEEN 178

  Fly   139 CRYKDILRTIE-YAASQNHSDSDCILVAILSHGEM----GYIY--AKDTQYKLDNIWSFFTANHC 196
            ...:|:...:. :|....|..||...:.::|||.:    |.::  .|......|.|:..|...:|
Human   179 LTARDMESALRAFATRPEHKSSDSTFLVLMSHGILEGICGTVHDEKKPDVLLYDTIFQIFNNRNC 243

  Fly   197 PSLAGKPKLFFIQACQGDR------LDGGVTMQ--RSQTETDGDSSMSYKIPVHADFLIAYSTVP 253
            .||..|||:..:|||:|..      .|...:::  .||:..:.:....||..|..||:...|:.|
Human   244 LSLKDKPKVIIVQACRGANRGELWVRDSPASLEVASSQSSENLEEDAVYKTHVEKDFIAFCSSTP 308

  Fly   254 GFYSWRNTTRGSWFMQSL---------CAELAANGKRLDILTLLTFVCQRVAVDFESCTPDTPEM 309
            ...|||::|.||.|:..|         |..|..             |.::|...||     ||
Human   309 HNVSWRDSTMGSIFITQLITCFQKYSWCCHLEE-------------VFRKVQQSFE-----TP-- 353

  Fly   310 HQQKQIPCITTM-LTR 324
            ..:.|:|.|..: :||
Human   354 RAKAQMPTIERLSMTR 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drice	NP_524551.2	CASc	86..330	CDD:214521	69/266 (26%)
CASP4	NP_001216.1	Required for LPS-binding. /evidence=ECO:0000250|UniProtKB:P70343	1..59
		CARD_CASP1-like	5..81	CDD:260036
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	84..104
		CASc	126..375	CDD:214521	69/266 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910