Protein Alignment Drice and CASP1

DIOPT Version :10

• Sequence 1: NP_524551.2
• Gene: Drice / 43514
• FlyBaseID: FBgn0019972
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: XP_016873882.2
• Gene: CASP1 / 834
• HGNCID: 1499
• Length: 448
• Species: Homo sapiens
• Alignment Length: 348
• Identity: 93/348 - (26%)
• Similarity: 142/348 - (40%)
• Gaps: 69/348 - (19%)

  Fly     7 GESADQVGIRVGNPEQPNDHTDALGSVGSGGAGSSGLVAGSSHPYGSGAIGQLANGYSSPSSSYR 71
            |.||||..   ||.....|....|.|..:..|    :....:.|..||:.|
Human   132 GLSADQTS---GNYLNMQDSQGVLSSFPAPQA----VQDNPAMPTSSGSEG-------------- 175

  Fly    72 KNV-------AKMVTDRHAAE-YNMRHKN--RGMALIFNHEHFEVPTLKSRAGTNVDCENLTRVL 126
             ||       |:.:..:.:|| |.:..|:  ..:|||..:|.|:  ::..|.|..||...:|.:|
Human   176 -NVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFD--SIPRRTGAEVDITGMTMLL 237

  Fly   127 KQLDFEVTVYKDCRYKDILRTIE-YAASQNHSDSDCILVAILSHG-EMGYIYAKDTQ-----YKL 184
            :.|.:.|.|.|:....|:...:| :|....|..||...:..:||| ..|....|.::     .:|
Human   238 QNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQL 302

  Fly   185 DNIWSFFTANHCPSLAGKPKLFFIQACQGDRLDGGVTMQRSQTETDGDSSMS----------YKI 239
            :.|::.....:||||..|||:..||||:||  ..||...:......|:.|:.          .|.
Human   303 NAIFNMLNTKNCPSLKDKPKVIIIQACRGD--SPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKA 365

  Fly   240 PVHADFLIAYSTVPGFYSWRNTTRGSWFMQSLCAELAANGKRLDILTLLTFVCQRVAVDFESCTP 304
            .:..||:...|:.|...|||:.|.||.|:..|...:.......|:..:.    ::|...||.  |
Human   366 HIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIF----RKVRFSFEQ--P 424

  Fly   305 DTPEMHQQKQIPCITT---MLTR 324
            |     .:.|:|  ||   .|||
Human   425 D-----GRAQMP--TTERVTLTR 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drice	NP_524551.2	CASc	86..330	CDD:214521	73/261 (28%)
CASP1	XP_016873882.2	DD	<77..131	CDD:472698
		CASc	197..446	CDD:214521	73/261 (28%)