DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drice and Casp2

DIOPT Version :9

Sequence 1:	NP_524551.2	Gene:	Drice / 43514	FlyBaseID:	FBgn0019972	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	XP_038964243.1	Gene:	Casp2 / 64314	RGDID:	69274	Length:	470	Species:	Rattus norvegicus

Alignment Length:	296	Identity:	84/296 - (28%)
Similarity:	134/296 - (45%)	Gaps:	39/296 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 LANGYSSPSSSYRKNVAKMVTDRHAAEYNMRHKNRGMALIFNHEHFE-VPTLKSRAGTNVDCENL 122
            |.||...|....:....:.....:...|.::.:.||:||:.::.||. ...|:.|:|.:||...|
  Rat   165 LDNGDGPPCLQVKPCTPEFYQAHYQLAYRLQSQPRGLALVMSNVHFTGEKDLEFRSGGDVDHTTL 229

  Fly   123 TRVLKQLDFEVTVYKDCR--------YKDILRTIEYAASQN-------------HSDSDCILVAI 166
            ..:.|.|.:.|.|..|..        |..|.:  :|...|.             |..:|..:||:
  Rat   230 VTLFKLLGYNVHVLYDQTAQFHRFQLYSGIYK--KYPKGQEMQEKLQNFAQLPAHRVTDSCIVAL 292

  Fly   167 LSHGEMGYIYAKDTQ-YKLDNIWSFFTANHCPSLAGKPKLFFIQACQGDRLDGGVTMQRSQT--- 227
            ||||..|.||..|.: .:|..::..|...:||||..|||:||||||:||..|.||..|..:.
  Rat   293 LSHGVEGGIYGVDGKLLQLQEVFRLFDNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHAQ 357

  Fly   228 -----ETDG--DSSMSYKIPVHADFLIAYSTVPGFYSWRNTTRGSWFMQSLCAELAANGKRLDIL 285
                 |:|.  :..|..::|..:|.:..|:.:.|..:.|||.||||::::|....:.....:.:.
  Rat   358 SPGCEESDAGKEELMKMRLPTRSDMICGYACLKGNAAMRNTKRGSWYIEALTQVFSERACDMHVA 422

  Fly   286 TLLTFVCQRVAVDFESCTPDTPEMHQQKQIP--CIT 319
            .:|..| ..:..:.|...|.| |.|:.|::.  |.|
  Rat   423 DMLVKV-NALIKEREGYAPGT-EFHRCKEMSEYCST 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drice	NP_524551.2	CASc	86..330	CDD:214521	80/269 (30%)
Casp2	XP_038964243.1	CARD_CASP2	32..118	CDD:260040
Casp2	XP_038964243.1	CASc	192..465	CDD:214521	80/269 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910