DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drice and Casp8

DIOPT Version :9

Sequence 1:	NP_524551.2	Gene:	Drice / 43514	FlyBaseID:	FBgn0019972	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_071613.1	Gene:	Casp8 / 64044	RGDID:	620945	Length:	482	Species:	Rattus norvegicus

Alignment Length:	248	Identity:	95/248 - (38%)
Similarity:	135/248 - (54%)	Gaps:	25/248 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 YNMRHKNRGMALIFNHEHF-----EVPTL---KSRAGTNVDCENLTRVLKQLDFEVTVYKDCRYK 142
            |.|:.|.||..||||:.:|     ::|.|   :.|.|||.|.|.|::..|:|.||:..:.||...
  Rat   228 YQMKSKPRGYCLIFNNNNFSKAREDIPKLSNMRDRKGTNYDEEALSKTFKELHFEIVSFSDCTAS 292

  Fly   143 DILRTIEYAASQNHSDSDCILVAILSHGEMGYIYAKD-TQYKLDNIWSFFTANHCPSLAGKPKLF 206
            .|...:....|::|...||.:..|||||:.|.:|..| .:..:..:.|:||.:.|||||||||:|
  Rat   293 QIHEVLVSYQSKDHKGKDCFICCILSHGDKGIVYGTDGKEASIYELTSYFTGSKCPSLAGKPKIF 357

  Fly   207 FIQACQGDRLDGGVTM-------QRSQTETDGDSSMSYKIPVHADFLIAYSTVPGFYSWRNTTRG 264
            |||||||:.....|.:       |....|.|..|..:| ||..||||:..:||....|:|:.|||
  Rat   358 FIQACQGNNFQKAVPVPDETGLEQEHVLEEDSSSYKNY-IPDEADFLLGMATVKNCVSYRDPTRG 421

  Fly   265 SWFMQSLCAELAANGKR-LDILTLLTFVCQRVAVDFESCTPDTPEMHQQKQIP 316
            :|::||||..|.....| .|||::||      .|:::....|.|. :..||:|
  Rat   422 TWYIQSLCQSLRERCPRGEDILSILT------GVNYDVSNKDNPR-NMGKQMP 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drice	NP_524551.2	CASc	86..330	CDD:214521	95/248 (38%)
Casp8	NP_071613.1	DED_Caspase_8_r1	3..84	CDD:260041
		DD	98..179	CDD:417479
		CASc	227..480	CDD:237997	95/248 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810