DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drice and Casp9

DIOPT Version :9

Sequence 1:	NP_524551.2	Gene:	Drice / 43514	FlyBaseID:	FBgn0019972	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_113820.1	Gene:	Casp9 / 58918	RGDID:	61867	Length:	454	Species:	Rattus norvegicus

Alignment Length:	383	Identity:	114/383 - (29%)
Similarity:	161/383 - (42%)	Gaps:	81/383 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 NNGESADQVGIRVGNPE--QPNDH--TDALGSVGSGGAGSSGLVAGSSHPYGSGAIGQLANGYSS 65
            ::|::|.|      :||  .|.||  ...||.:|........:....|.|    |:|.|......
  Rat    91 SSGQAAKQ------DPEAVTPLDHLVPVVLGPMGLKSKEQKVVKLDPSQP----ALGNLTPVVLG 145

  Fly    66 PSSSY----RKNVAKMVT--------------------DRHA-AEYNMRHKNRGMALIFNHEHFE 105
            |...:    |..|....|                    :||| ..|.:.....|..||.|:.:|
  Rat   146 PEELWPTRLRPEVLTPETPRPVDIGSGRAHDVCTPGKIERHADMAYTLDSDPCGHCLIINNVNF- 209

  Fly   106 VPT--LKSRAGTNVDCENLTRVLKQLDFEVTVYKDCRYKDILRTIEYAASQNHSDSDCILVAILS 168
            .|:  |.:|.|::||||.|......|.|.|.|..|...|.::..:...|.::|...||.:|.|||
  Rat   210 CPSSGLSTRIGSHVDCEKLQHRFCWLRFMVEVKNDLTAKKMVTALMEMAHRDHRALDCFVVVILS 274

  Fly   169 HGEM-------GYIYAKD-TQYKLDNIWSFFTANHCPSLAGKPKLFFIQACQGDRLDGG--VTMQ 223
            ||..       |.:|..| ....::.|.:.|....||||.|||||||||||.|::.|.|  |...
  Rat   275 HGCQASHLQFPGAVYGTDGCSVSIERIVNIFNGTGCPSLGGKPKLFFIQACGGEQKDHGFEVAFT 339

  Fly   224 RSQTET-DGDS---SMSYK--------------IPVHADFLIAYSTVPGFYSWRNTTRGSWFMQS 270
            .||.:. |.||   ::.|:              :|..:|.|::|||.|||.|||:...|||::::
  Rat   340 SSQDKAFDSDSEPDAVPYQEGPRTLDQLDAVSSLPTPSDILVSYSTFPGFVSWRDKKSGSWYIET 404

  Fly   271 LCAELAANGKRLDILTLLTFVCQRVAVDFESCTPDTPEMHQQKQIPCITTMLTRILRF 328
            |...|....:..|:.:||..|...|:           |....||||.....|.:.|.|
  Rat   405 LDGVLEQWARSEDLQSLLLRVANAVS-----------EKGVYKQIPGCFNFLRKKLFF 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drice	NP_524551.2	CASc	86..330	CDD:214521	91/273 (33%)
Casp9	NP_113820.1	CARD_CASP9	19..90	CDD:176740
Casp9	NP_113820.1	CASc	190..452	CDD:237997	91/274 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010