DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drice and casp3b

DIOPT Version :9

Sequence 1:	NP_524551.2	Gene:	Drice / 43514	FlyBaseID:	FBgn0019972	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_001041531.2	Gene:	casp3b / 566604	ZFINID:	ZDB-GENE-070607-1	Length:	285	Species:	Danio rerio

Alignment Length:	284	Identity:	107/284 - (37%)
Similarity:	153/284 - (53%)	Gaps:	24/284 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 SSHPYGSGAIGQLANGYSSPSSSYRKNVAKMVTDRHAAEYNMRHKNRGMALIFNHEHFEVPT-LK 110
            ||.....|.:...|..:|..:..|              :|...:.|.|..||.|:::|...| :.
Zfish    22 SSSVTDPGLVQMDAKSHSDDNVDY--------------QYKTNYPNLGQCLIINNKNFHKRTGMG 72

  Fly   111 SRAGTNVDCENLTRVLKQLDFEVTVYKDCRYKDILRTIEYAASQNHSDSDCILVAILSHGEMGYI 175
            .|.||:.|.:.:.....||.|:|..|.|.....::..:..|:.::||.|......:||||:.|.|
Zfish    73 VRNGTDEDAKKVFETFSQLGFKVGHYNDLTVSQMMALLNKASQEDHSKSAMFACVLLSHGDDGLI 137

  Fly   176 YAKDTQYKLDNIWSFFTANHCPSLAGKPKLFFIQACQGDRLDGGVTMQRSQTETDG-DSSMSYKI 239
            |..|...:|..:::.|..:.|.||.|||||||||||:|..||.|:       |.|| ....:.:|
Zfish   138 YGTDNSIELKRLFAHFRGDRCTSLVGKPKLFFIQACRGTDLDSGI-------ECDGVGDEETQRI 195

  Fly   240 PVHADFLIAYSTVPGFYSWRNTTRGSWFMQSLCAELAANGKRLDILTLLTFVCQRVAVDFESCTP 304
            ||.||||.||||.||:|:|||...||||:.|||..|...||:|:|:.::|.|..:||::||| :.
Zfish   196 PVEADFLYAYSTAPGYYAWRNVANGSWFISSLCDMLLKYGKQLEIMQVMTRVNHKVALEFES-SS 259

  Fly   305 DTPEMHQQKQIPCITTMLTRILRF 328
            :.|....:||||||.:|||:.|.|
Zfish   260 NLPGFDGKKQIPCIVSMLTKELYF 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drice	NP_524551.2	CASc	86..330	CDD:214521	101/245 (41%)
casp3b	NP_001041531.2	CASc	47..284	CDD:237997	101/245 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580502
Domainoid	1	1.000	200	1.000	Domainoid score	I2984
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	209	1.000	Inparanoid score	I3655
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D417543at33208
OrthoFinder	1	1.000	-	-		FOG0000242
OrthoInspector	1	1.000	-	-		mtm6547
orthoMCL	1	0.900	-	-		OOG6_103710
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3066
SonicParanoid	1	1.000	-	-		X460
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.690