DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drice and caspbl

DIOPT Version :9

Sequence 1:	NP_524551.2	Gene:	Drice / 43514	FlyBaseID:	FBgn0019972	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_001139064.1	Gene:	caspbl / 566185	ZFINID:	ZDB-GENE-090311-53	Length:	409	Species:	Danio rerio

Alignment Length:	347	Identity:	83/347 - (23%)
Similarity:	151/347 - (43%)	Gaps:	77/347 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 NPEQP----NDHTDALGSVGSGGAGSSGLV------------------AGSSHPYGSGAIGQLAN 61
            |||.|    ...:|.|..:.|......|::                  :.|.|.|....:    :
Zfish   100 NPEDPQSINTSGSDELEPIQSDWQRPRGIINRFQEFKTRLLYANRDDASISIHFYKQNTL----S 160

  Fly    62 GYSSPSSSYRKNVAKMVTDRHAAEYNMRHKNRGMALIFNHEHFEVPTLKSRAGTNVDCENLTRVL 126
            .|:..|.:.||.:|.::|:                ::|.::.      ..|||...|.||:..:|
Zfish   161 IYTPVSRTQRKGLALLITN----------------ILFANKQ------DDRAGAERDEENMEWLL 203

  Fly   127 KQLDFEVTVYKDCRYKDILRTI-EYAASQNHSDSDCILVAILSHGE------------MGYIYAK 178
            |.|:|.|..|::....:|.|.: :::....|.|:|...|.|:|||:            ..::..:
Zfish   204 KNLNFMVIKYRNLTGNEISRAVQDFSRRHEHQDADSTFVVIMSHGDRIQNKDAILGVNYNWLQNR 268

  Fly   179 DTQYKLDNIWSFFTANHCPSLAGKPKLFFIQACQGDRLDGGVTMQRSQTETDGDSSMSYKIPVHA 243
            :..|.:::.:|...:.:||:|..|||:..||||:|.:| |||.::....|:|   |..:|   ..
Zfish   269 NDVYFVEDTFSHLNSVNCPALIDKPKVILIQACRGGQL-GGVPVKDCVPESD---SWVHK---EK 326

  Fly   244 DFLIAYSTVPGFYSWRNTTRGSWFMQSLCAELAANGKRLDILTLLTFVCQRVAVDFESCTPDTPE 308
            ||:...||:|...::|:..:||:|:..:.....::..:..|:.|.    ::||...|.   |...
Zfish   327 DFVCFMSTMPDVVAYRDEVKGSYFISYIVDVFCSSACKDHIMELF----RKVAARMEK---DERF 384

  Fly   309 MHQQKQIPCI--TTMLTRILRF 328
            ..|.|.:|||  |:::.:...|
Zfish   385 RRQAKLLPCIERTSLVKKFYLF 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drice	NP_524551.2	CASc	86..330	CDD:214521	66/258 (26%)
caspbl	NP_001139064.1	Pyrin_ASC-like	5..84	CDD:260033
caspbl	NP_001139064.1	CASc	167..406	CDD:237997	69/274 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010