DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drice and casp10

DIOPT Version :9

Sequence 1:	NP_524551.2	Gene:	Drice / 43514	FlyBaseID:	FBgn0019972	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	XP_031748482.1	Gene:	casp10 / 548432	XenbaseID:	XB-GENE-480459	Length:	536	Species:	Xenopus tropicalis

Alignment Length:	276	Identity:	97/276 - (35%)
Similarity:	146/276 - (52%)	Gaps:	37/276 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 SSYRKNVAKMVTDRHAAE-YNMRHKNRGMALIFNHEHFEVPTLKS--RAGTNVDCENLTRVLKQL 129
            |..|.| ::|....:..| |:|.||:||..||.::..|    :|.  |.|::.|...|:.|...|
Frog   266 SDLRLN-SEMTPQANKEEFYDMNHKHRGYCLIIDNSVF----MKGNRREGSDKDAGALSDVFSWL 325

  Fly   130 DFEVTVYKDCRYKDILRTIEYAASQNHSDSDCILVAILSHGEMGYIY-AKDTQYKLDNIWSFFTA 193
            ..||.::::...:.|...::...|::||:.||.:..||:|||.|.:. :.|.:..:..|.|:|||
Frog   326 GLEVDIFENLMSEQIRDCLKRFKSRDHSERDCFVCCILTHGESGTVMGSDDKEVSIREIMSYFTA 390

  Fly   194 NHCPSLAGKPKLFFIQACQGDRLDGGVTMQRSQTETDG---DSSMSY--KIPVHADFLIAYSTVP 253
            ..|.||..||||||||||||.     .|...|:.|.|.   :.:..|  .:|..||||:..|||.
Frog   391 ISCTSLVLKPKLFFIQACQGK-----FTHPSSKVEADAIVPEENKKYVVNVPKDADFLLGMSTVD 450

  Fly   254 GFYSWRNTTRGSWFMQSLC---AELAANGKRLDILTLLTFVCQRVAVDFESCTPDTPEMHQQ--- 312
            |:.::|:|..|||::|:||   .||...|:  |||.:||.|.:.|::          :..||
Frog   451 GYAAYRHTREGSWYIQALCKNLVELVPRGE--DILAILTKVNKDVSL----------KEGQQGIL 503

  Fly   313 KQIPCITTMLTRILRF 328
            ||:|..:..|.:.|||
Frog   504 KQMPQPSYTLLKKLRF 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drice	NP_524551.2	CASc	86..330	CDD:214521	92/257 (36%)
casp10	XP_031748482.1	DD	1..82	CDD:417479
		DED_Caspase_10_r2	116..191	CDD:260074
		CASc	283..520	CDD:237997	92/258 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000