DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drice and casp9

DIOPT Version :9

Sequence 1:	NP_524551.2	Gene:	Drice / 43514	FlyBaseID:	FBgn0019972	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_001007405.2	Gene:	casp9 / 492763	ZFINID:	ZDB-GENE-030825-5	Length:	436	Species:	Danio rerio

Alignment Length:	309	Identity:	96/309 - (31%)
Similarity:	142/309 - (45%)	Gaps:	55/309 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 YSSPSSSYRKNVAKMVTDRHAAE--YNMRHKNRGMALIFNHEHFE-VPTLKSRAGTNVDCENLTR 124
            ||.||    :.|.:....|..:.  |.|.....|:.||.|:.:|| ...|..|.|:|:||:.|.:
Zfish   143 YSPPS----ETVVRPTRPRRDSIQCYKMDASPCGVCLIINNINFEKASELNDRKGSNIDCDKLEK 203

  Fly   125 VLKQLDFEVTVYKDCRYKDILRTIEYAASQNHSDSDCILVAILSHGE-------MGYIYAKD-TQ 181
            ..|.|:|||||.::.:.|.|...:...|.::||..||.:|.|||||.       .|.::..| ..
Zfish   204 RFKALNFEVTVKRNLKSKRIRHEMASLAKKDHSTYDCCVVIILSHGTEASHNRFPGAVHGVDGPA 268

  Fly   182 YKLDNIWSFFTANHCPSLAGKPKLFFIQACQGDRLD--------------GGV------------ 220
            ..:..|.::....:||||.|||||||||||.|...|              ||:
Zfish   269 VPIQIITNYLNGQNCPSLQGKPKLFFIQACGGGEKDIGFEVSPDDVQPSIGGIDDEMDAIPMSSS 333

  Fly   221 --TMQRSQTETDGDSSMSYKIPVHADFLIAYSTVPGFYSWRNTTRGSWFMQSLCAELAANGKRLD 283
              ::..:..|.|..:|    :|..:|.|::|||.||:.|||:|..|||::::|...|..|....|
Zfish   334 SDSLSTASDELDARAS----LPTPSDILVSYSTFPGYVSWRDTEAGSWYVENLDRVLEENAITDD 394

  Fly   284 ILTLLTFVCQRVAVDFESCTPDTPEMHQQKQIPCITTMLTRILRFSDKQ 332
            ::|:|..|...|:        ........||:|.....|.::|.|...|
Zfish   395 LVTMLMLVNDAVS--------QISAKGLYKQMPGSFNFLRKLLYFQSSQ 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drice	NP_524551.2	CASc	86..330	CDD:214521	89/280 (32%)
casp9	NP_001007405.2	CARD_CASP9	5..88	CDD:176740
casp9	NP_001007405.2	CASc	163..432	CDD:237997	88/280 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910