DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drice and csp-1

DIOPT Version :9

Sequence 1:	NP_524551.2	Gene:	Drice / 43514	FlyBaseID:	FBgn0019972	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_001022452.1	Gene:	csp-1 / 175007	WormBaseID:	WBGene00000819	Length:	536	Species:	Caenorhabditis elegans

Alignment Length:	290	Identity:	83/290 - (28%)
Similarity:	140/290 - (48%)	Gaps:	42/290 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 YSSPSSSYRKNVAKMVTDRHAAEYNMRHKNRGMALIFNHEHFEVPTLKSRAGTNVDCENLTRVLK 127
            |.|.|...|.: ||....:|...|.|....||..||.::|:|:  .::.|.||..|..|||::.:
Worm   263 YDSQSRMPRTD-AKKSNHKHKYCYEMNSNPRGTVLILSNENFK--NMERRVGTKQDEVNLTKLFQ 324

  Fly   128 QLDFEVTVYKDCRYKDILRTIEYAASQNHSDSDCILVAILSHGE-MGYIYAKDTQYKLDNIW--S 189
            :|.:.|...::...:.:|..|:..|...|:||  |::.:||||: .|.::..|....  |:.  |
Worm   325 KLQYTVICKRNLEAESMLEAIKEFAEMAHTDS--IILFLLSHGDGAGSVFGIDDMPV--NVMEVS 385

  Fly   190 FFTANHCPSLAGKPKLFFIQACQGDRLDGGVTMQRSQTETDG---------------DSSMSYKI 239
            .:.|.| .:|..|||...:.||:|.:|:.||.:       ||               :..||..:
Worm   386 TYLAYH-QNLLLKPKWVAVSACRGGKLNMGVPV-------DGLPALEDKCAPISKFWNLMMSRIM 442

  Fly   240 P-----VHADFLIAYSTVPGFYSWRNTTRGSWFMQSLCAELAANGKRLDILTLLTFVCQRVAVDF 299
            |     ::||.:|::||..||.|:|:...|:|:::|:|.....:.|.:.:|.:||...:.|...:
Worm   443 PGTFTSLNADVIISFSTTDGFTSYRDEEAGTWYIKSMCKVFNKHSKTMHLLDILTETGRNVVTKY 507

  Fly   300 ESCTPDTPEMHQQKQIPCITTMLTRILRFS 329
            |:...:.    ..||.|.|.:.||:...||
Worm   508 ENVQGNV----VLKQAPEILSRLTKQWHFS 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drice	NP_524551.2	CASc	86..330	CDD:214521	76/267 (28%)
csp-1	NP_001022452.1	SPK	76..188	CDD:214732
csp-1	NP_001022452.1	CASc	285..533	CDD:214521	74/265 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	130	1.000	Domainoid score	I3239
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5027
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D417543at33208
OrthoFinder	1	1.000	-	-		FOG0000242
OrthoInspector	1	1.000	-	-		mtm4766
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.870