DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drice and Casp3

DIOPT Version :9

Sequence 1:	NP_524551.2	Gene:	Drice / 43514	FlyBaseID:	FBgn0019972	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_001271338.1	Gene:	Casp3 / 12367	MGIID:	107739	Length:	277	Species:	Mus musculus

Alignment Length:	247	Identity:	105/247 - (42%)
Similarity:	152/247 - (61%)	Gaps:	8/247 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 AEYNMRHKNRGMALIFNHEHFEVPT-LKSRAGTNVDCENLTRVLKQLDFEVTVYKDCRYKDILRT 147
            :.|.|.:...|:.:|.|:::|...| :.||:||:||..||......|.::|....|...:|||..
Mouse    35 SSYKMDYPEMGICIIINNKNFHKSTGMSSRSGTDVDAANLRETFMGLKYQVRNKNDLTREDILEL 99

  Fly   148 IEYAASQNHSDSDCILVAILSHGEMGYIYAKDTQYKLDNIWSFFTANHCPSLAGKPKLFFIQACQ 212
            ::..:.::||.....:..|||||:.|.||..:...:|..:.|||..::|.||.||||||.||||:
Mouse   100 MDSVSKEDHSKRSSFVCVILSHGDEGVIYGTNGPVELKKLTSFFRGDYCRSLTGKPKLFIIQACR 164

  Fly   213 GDRLDGGVTMQRSQTETDGDSSMS-YKIPVHADFLIAYSTVPGFYSWRNTTRGSWFMQSLCAELA 276
            |..||.|:     :|::..|..|: .||||.||||.||||.||:|||||:..||||:||||:.|.
Mouse   165 GTELDCGI-----ETDSGTDEEMACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCSMLK 224

  Fly   277 ANGKRLDILTLLTFVCQRVAVDFESCTPDTPEMHQQKQIPCITTMLTRILRF 328
            ....:|:.:.:||.|.::||.:|||.:.|: ..|.:||||||.:|||:.|.|
Mouse   225 LYAHKLEFMHILTRVNRKVATEFESFSLDS-TFHAKKQIPCIVSMLTKELYF 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drice	NP_524551.2	CASc	86..330	CDD:214521	105/245 (43%)
Casp3	NP_001271338.1	CASc	37..277	CDD:214521	105/245 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836968
Domainoid	1	1.000	202	1.000	Domainoid score	I2975
eggNOG	1	0.900	-	-		E1_KOG3573
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	208	1.000	Inparanoid score	I3679
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D417543at33208
OrthoFinder	1	1.000	-	-		FOG0000242
OrthoInspector	1	1.000	-	-		mtm8756
orthoMCL	1	0.900	-	-		OOG6_103710
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3066
SonicParanoid	1	1.000	-	-		X460
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.690