DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drice and casp1

DIOPT Version :9

Sequence 1:	NP_524551.2	Gene:	Drice / 43514	FlyBaseID:	FBgn0019972	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	XP_012813105.2	Gene:	casp1 / 100491605	XenbaseID:	XB-GENE-485195	Length:	408	Species:	Xenopus tropicalis

Alignment Length:	225	Identity:	68/225 - (30%)
Similarity:	107/225 - (47%)	Gaps:	32/225 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 YNMRHK--NRGMALIFNHEHFEVPTLKSRAGTNVDCENLTRVLKQLDFEVTVYKDCRYKDILRTI 148
            |.||.:  .:.:|||..:|.||  ||..|.|..||.:.:|::|.:|.::|....:...:::|:.:
Frog   158 YEMRKREGRKRLALIICNEKFE--TLTERQGAKVDLDGMTKLLNELGYQVLQETNLAKEEMLKVL 220

  Fly   149 -EYAASQNHSDSDCILVAILSHGEMGYIYAKDTQ--------------YKLDNIWSFFTANHCPS 198
             |:||.:.|.|||...:.::|||:...:...|::              .:.|.|:|.|...|||.
Frog   221 KEFAAREEHVDSDSTFIVLMSHGDKPGVCGTDSKKIEHEKGQCQVTNLLQTDEIFSIFNNIHCPK 285

  Fly   199 LAGKPKLFFIQACQGDR------LDGGVTMQRSQTETDGDSSMSYKIPVHADFLIAYSTVPGFYS 257
            |..|||:..||||:|:.      .|........|.|.|.    .:::....||:...|:.|...|
Frog   286 LRDKPKVIIIQACRGEERGQKLVCDAVALPPEEQLEDDA----LHRVQRETDFICFCSSTPDTVS 346

  Fly   258 WRNTTRGSWFMQSLCA---ELAANGKRLDI 284
            ||:.|.||.|:..|..   |||.....:||
Frog   347 WRHPTMGSLFITGLIKKMNELAHCQPLMDI 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drice	NP_524551.2	CASc	86..330	CDD:214521	68/225 (30%)
casp1	XP_012813105.2	DD	4..86	CDD:417479
casp1	XP_012813105.2	CASc	158..406	CDD:214521	68/225 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100