DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drice and casp2

DIOPT Version :9

Sequence 1:	NP_524551.2	Gene:	Drice / 43514	FlyBaseID:	FBgn0019972	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	XP_012809163.2	Gene:	casp2 / 100486813	XenbaseID:	XB-GENE-482390	Length:	421	Species:	Xenopus tropicalis

Alignment Length:	258	Identity:	87/258 - (33%)
Similarity:	131/258 - (50%)	Gaps:	17/258 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 HAAEYNMRHKNRGMALIFNHEHFEVPTLKSRAGTNVDCENLTRVLKQLDFEVTVYKDCRYKDILR 146
            |...|.|....||.|||.::..||...|..|.|..||..:|.::...|.|:|.|.::...::::.
Frog   158 HQQAYKMHSCPRGRALIISNVAFETQDLDHRYGGEVDVASLEKLFSSLGFQVEVRRNLNAQNMMS 222

  Fly   147 TI-EYAASQNHSDSDCILVAILSHGEMGYIYAKDTQYKLDNIWSFFTA---NHCPSLAGKPKLFF 207
            .: .::|...||..|..:||:||||..|.:|..|.  ||..:...|||   .|||.|..|||:||
Frog   223 QLGAFSALPAHSALDSCVVAVLSHGLDGAVYGTDG--KLVQLQDVFTAMDNAHCPQLQNKPKMFF 285

  Fly   208 IQACQGDRLDGGVTMQ--RSQT------ETD-GDSSMSYKIPVHADFLIAYSTVPGFYSWRNTTR 263
            ||||:|:..|.||..:  |.|:      ::| |...:..::|..:|.:.||:.:.|..|.|||.|
Frog   286 IQACRGEEADRGVDQRDGREQSASPGCEQSDAGREDIKVRLPTQSDMICAYACLKGTVSLRNTKR 350

  Fly   264 GSWFMQSLCAELAANGKRLDILTLLTFVCQRVAVDFESCTPDTPEMHQQKQIPCITTMLTRIL 326
            ||||:|.|.:..:...|...:..:|..| ..:..:.|...|.| |.|:.|::....:.|.|.|
Frog   351 GSWFVQDLVSVFSQYSKNTHVADMLVKV-NALIKEREGHAPGT-EFHRCKEMSEYCSTLCRDL 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drice	NP_524551.2	CASc	86..330	CDD:214521	86/254 (34%)
casp2	XP_012809163.2	DD	5..86	CDD:417479
casp2	XP_012809163.2	CASc	161..414	CDD:237997	86/255 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10454
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010