Protein Alignment sro and BDH1

DIOPT Version :10

• Sequence 1: NP_651725.1
• Gene: sro / 43512
• FlyBaseID: FBgn0262112
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: XP_011511369.1
• Gene: BDH1 / 622
• HGNCID: 1027
• Length: 347
• Species: Homo sapiens
• Alignment Length: 333
• Identity: 97/333 - (29%)
• Similarity: 153/333 - (45%)
• Gaps: 33/333 - (9%)

  Fly     7 LRALRRSLGLGRQQL-------------KVDSRHVVLITGCDSGLGHSMAVYCHESLHMTVISCC 58
            |..:||.|.||....             .|.|: .||:||||||.|.|:|.:.|....:....|.
Human    28 LGEMRRPLLLGSTSFIPIGRRTYASAAEPVGSK-AVLVTGCDSGFGFSLAKHLHSKGFLVFAGCL 91

  Fly    59 HNIKS-EGAKLLQGLASAKDGLSRMHTLELDLLEPDSIRLVHRQLRDILAKDPSYRLTALINNAG 122
            ...|. :|.|.|..|.|     .|:.|::|::...:.:..|...:|..| |||...:..|:||||
Human    92 MKDKGHDGVKELDSLNS-----DRLRTVQLNVCSSEEVEKVVEIVRSSL-KDPEKGMWGLVNNAG 150

  Fly   123 VMCFGEFEWQLTEQIEAQINCNLLGTMRLTHELLPLLRQQQGRIINVTSHCGLQALPALGPYAAS 187
            :..|||.|:...|..:.....||.||:|:|...|||:|:.:||::|::|..|..|.||..||..:
Human   151 ISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCIT 215

  Fly   188 KAALRFWTDSLRVELQQYGMEVVNFIPGSFVLDSNIAARQ--QQHAQKMREAFSAEQHALYDTYF 250
            |..:..::|.||.|:...|::|....||:|:..:::.:.:  |..|:||.|.........|...:
Human   216 KFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKY 280

  Fly   251 EAFNGYLKVLSGFKPPNRLRNESLLAKFKDALTSSQPLALYIEEPRRYRLYRWL----FTLCPTP 311
              |:..:..:..:..........::.....|||::.|...|  .|..|  |.||    .|..|..
Human   281 --FDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTPYTRY--HPMDY--YWWLRMQIMTHLPGA 339

  Fly   312 LVDWLTVR 319
            :.|.:.:|
Human   340 ISDMIYIR 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sro	NP_651725.1	17beta-HSD-like_SDR_c	27..300	CDD:187632	82/275 (30%)
BDH1	XP_011511369.1	type2_17beta_HSD-like_SDR_c	60..345	CDD:187665	88/297 (30%)