Protein Alignment sro and HSD17B11

DIOPT Version :9

• Sequence 1: NP_651725.1
• Gene: sro / 43512
• FlyBaseID: FBgn0262112
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_057329.3
• Gene: HSD17B11 / 51170
• HGNCID: 22960
• Length: 300
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 67/270 - (24%)
• Similarity: 111/270 - (41%)
• Gaps: 43/270 - (15%)

  Fly    28 VVLITGCDSGLGHSMAVYCHESLHMTVISCCHNIKSEGAKLLQGLASAKDGL-SRMHTLELDLLE 91
            :|||||...|:|. :..|....|...::  ..:|...|   |:..|:...|| :::||..:|...
Human    38 IVLITGAGHGIGR-LTAYEFAKLKSKLV--LWDINKHG---LEETAAKCKGLGAKVHTFVVDCSN 96

  Fly    92 PDSI----RLVHRQLRDILAKDPSYRLTALINNAGVMCFGEFEWQLTEQIEAQINCNLLGTMRLT 152
            .:.|    :.|..::.|:         :.|:|||||:...:.......|||.....|:|.....|
Human    97 REDIYSSAKKVKAEIGDV---------SILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTT 152

  Fly   153 HELLP-LLRQQQGRIINVTSHCGLQALPALGPYAASK-AALRF---WTDSLRVELQQYGMEVV-- 210
            ...|| :.:...|.|:.|.|..|..::|.|..|.:|| ||:.|   .||.| ..||..|::..
Human   153 KAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDEL-AALQITGVKTTCL 216

  Fly   211 --NFIPGSFVLDSNIA----ARQQQHAQKMREAFSAEQHALYDTYFEAFNGYLKVLSGFKPPNRL 269
              ||:...|:.:.:.:    ...::...::......||..::.....||...|:         |:
Human   217 CPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTTLE---------RI 272

  Fly   270 RNESLLAKFK 279
            ..|..||..|
Human   273 LPERFLAVLK 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sro	NP_651725.1	17beta-HSD-like_SDR_c	27..300	CDD:187632	67/270 (25%)
		adh_short	28..229	CDD:278532	57/218 (26%)
HSD17B11	NP_057329.3	17beta-HSDXI-like_SDR_c	38..277	CDD:187598	64/263 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910