Protein Alignment sro and RDH8

DIOPT Version :9

• Sequence 1: NP_651725.1
• Gene: sro / 43512
• FlyBaseID: FBgn0262112
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_056540.3
• Gene: RDH8 / 50700
• HGNCID: 14423
• Length: 311
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 85/323 - (26%)
• Similarity: 127/323 - (39%)
• Gaps: 50/323 - (15%)

  Fly    29 VLITGCDSGLGHSMAVYCHESLHMTVISCCHNIKSEGAKLLQGLASAKDGLSRMHTLELDLLEPD 93
            |||:||.||:|..:||           ...|:.|    |..|.:|:.:| |.:..|||....|..
Human     8 VLISGCSSGIGLELAV-----------QLAHDPK----KRYQVVATMRD-LGKKETLEAAAGEAL 56

  Fly    94 SIRLVHRQLRDILAKDPSY---------RLTALINNAGVMCFGEFEWQLTEQIEAQINCNLLGTM 149
            ...|...|| |: ..|.|.         .:..|:||||:...|..|......::...:.|..|.:
Human    57 GQTLTVAQL-DV-CSDESVAQCLSCIQGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAV 119

  Fly   150 RLTHELLP-LLRQQQGRIINVTSHCGLQALPALGPYAASKAALRFWTDSLRVELQQYGMEVVNFI 213
            ||...:|| :.|::||.|:.::|..|||.:.....|||||.||..:.:||.::|.|:.:.:....
Human   120 RLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFISLVE 184

  Fly   214 PGSFVLDSNIAARQQQHAQKMREAFSAEQHALYDTYFEA---------------FNGYLKVLSGF 263
            ||..|.:.......|....:.........|...|.|..|               ....:.|:|..
Human   185 PGPVVTEFEGKLLAQVSMAEFPGTDPETLHYFRDLYLPASRKLFCSVGQNPQDVVQAIVNVISST 249

  Fly   264 KPPNRLRNESLLAKFKDALTSSQPLALYIEEPRRYRLYRWLFTLCPTPLVDWLTVRFC-AMPT 325
            :||.|.:.....:......|.....:||:....|. |:|     ||..|...|....| .:||
Human   250 RPPLRRQTNIRYSPLTTLKTVDSSGSLYVRTTHRL-LFR-----CPRLLNLGLQCLSCGCLPT 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sro	NP_651725.1	17beta-HSD-like_SDR_c	27..300	CDD:187632	76/295 (26%)
		adh_short	28..229	CDD:278532	62/209 (30%)
RDH8	NP_056540.3	type1_17beta-HSD-like_SDR_c	6..262	CDD:187666	72/271 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910