Protein Alignment sro and rdh5

DIOPT Version :10

• Sequence 1: NP_651725.1
• Gene: sro / 43512
• FlyBaseID: FBgn0262112
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_001011363.1
• Gene: rdh5 / 496830
• XenbaseID: XB-GENE-1011657
• Length: 319
• Species: Xenopus tropicalis
• Alignment Length: 325
• Identity: 90/325 - (27%)
• Similarity: 138/325 - (42%)
• Gaps: 60/325 - (18%)

  Fly    18 RQQLKVDSRHVVLITGCDSGLGHSMAVYCHESLHMTVISCCHNIKSEGAKLLQGL---ASAKDGL 79
            ||::...|...|.|||||:|.|:.:|               ..:..:|.::|.|.   |.|.|..
 Frog    21 RQKISRFSNKHVFITGCDTGFGNLLA---------------KRLSRKGFQVLAGCLTQAGADDLQ 70

  Fly    80 SRMHT-LELDLLEPDSIRLVHRQLRDILAKDPSYRLTALINNAGVM-CFGEFEWQLTEQIEAQIN 142
            ....| |:..||:..|...:::.:..:.::.....|..|:||||:. ..|..||...:..:..::
 Frog    71 KACPTGLKCTLLDVTSQESINKAVEWVKSEVGDRGLYGLVNNAGIANPIGPTEWMTIQDYKRVMD 135

  Fly   143 CNLLGTMRLTHELLPLLRQQQGRIINVTSHCGLQALPALGPYAASKAALRFWTDSLRVELQQYGM 207
            .|..||:.::...|.|:::.||||||:.|..|..:... |.|..||.|:..::||||.::|.:|:
 Frog   136 VNAFGTIAVSLSFLSLIKKAQGRIINMASILGRISANG-GGYCVSKYAVEAFSDSLRRDMQHFGV 199

  Fly   208 EVVNFIPGSFV-----LDSNIAARQQQHAQKMREAFSAEQHALY-DTYFEAFNGYLKVLSGFKPP 266
            .|....||.|.     |||     .::..|.:.:....|....| |.||:.   ||||
 Frog   200 RVCIIEPGFFKTAVTNLDS-----IERSLQLLWDQMPPETKMTYGDKYFQQ---YLKV------- 249

  Fly   267 NRLRNESLLAKF-KDALTSSQPL----ALYIEEPRRYRLYRWLFTLCPTPLVDWLTVRFCAMPTY 326
                 :.|:..| .||..|..|.    ||....||......|     ...|| ||...:  ||.:
 Frog   250 -----QRLIMNFICDADISKVPKCIEHALQARYPRTRYSPGW-----DAKLV-WLPASY--MPAF 301

  Fly   327  326
             Frog   302  301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sro	NP_651725.1	17beta-HSD-like_SDR_c	27..300	CDD:187632	80/288 (28%)
rdh5	NP_001011363.1	Rossmann-fold NAD(P)(+)-binding proteins	30..307	CDD:473865	87/316 (28%)