DRSC/TRiP Functional Genomics Resources

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Protein Alignment sro and hsd17b6

DIOPT Version :9

Sequence 1:NP_651725.1 Gene:sro / 43512 FlyBaseID:FBgn0262112 Length:335 Species:Drosophila melanogaster
Sequence 2:NP_001011296.1 Gene:hsd17b6 / 496749 XenbaseID:XB-GENE-5821225 Length:318 Species:Xenopus tropicalis


Alignment Length:325 Identity:92/325 - (28%)
Similarity:148/325 - (45%) Gaps:40/325 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 RQQLKVD--SRHVVLITGCDSGLGHSMAVYCHESLHMTVISCCHNIKSEGAKLLQGLASAKDGLS 80
            ||:.|:.  |...|.|||||||.|:.:|... :...:.|::.|  :..:||:.|:...|     |
 Frog    19 RQRKKIQNLSDKYVFITGCDSGFGNVLAKQL-DKQGIQVLATC--LTEKGAETLKSETS-----S 75

  Fly    81 RMHTLELDLLEPDSIRLVHRQLRDILAKDPSYRLTALINNAGV-MCFGEFEWQLTEQIEAQINCN 144
            |:.|:.:::.:..|::.....:..|:.   ...|..|:||||. ..|....||..|.....:..|
 Frog    76 RLRTVNMNVTDSQSVKSAAEWVTGIVG---DAGLWGLVNNAGYGFVFSPTGWQTKEHFVKVLEIN 137

  Fly   145 LLGTMRLTHELLPLLRQQQGRIINVTSHCGLQALPALGPYAASKAALRFWTDSLRVELQQYGMEV 209
            |||.:.:|..||||||:.||||:||:|:.|..|... |.|..||..:..::||||.||..:|::|
 Frog   138 LLGMVDVTLNLLPLLRKAQGRIVNVSSNAGRLAFIG-GGYCLSKFGVEAFSDSLRRELLDFGIKV 201

  Fly   210 VNFIPGSFVLDSNIAARQQQHAQKMREAFSAEQHALY-DTYFEAFNGYLKVLSGFKPPNRLRNES 273
            ....||:|.....::....|..:::......|....| :.|::.:...:..|:....|.      
 Frog   202 SIIEPGAFRTGMGVSGPHLQFLEQLWNNLDPETKKSYGEKYYQQYFQNVACLTSMTSPK------ 260

  Fly   274 LLAKFKD----ALTSSQPLALYIEEPRRY------RLYRWLFTLCPTPLVDWLTVRFCAMPTYES 328
             |.|..|    |||:..|..       ||      :||....:..||.:.|::..|....|.:.:
 Frog   261 -LHKVTDCMEHALTAVHPWT-------RYSVGWDCKLYHLPLSYLPTAVSDYVLCRSAPKPAHSA 317

  Fly   329  328
             Frog   318  317

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
sroNP_651725.1 17beta-HSD-like_SDR_c 27..300 CDD:187632 81/284 (29%)
adh_short 28..229 CDD:278532 66/201 (33%)
hsd17b6NP_001011296.1 NADB_Rossmann 30..306 CDD:389744 86/301 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D370032at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.010

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