Protein Alignment sro and rdh1

DIOPT Version :10

• Sequence 1: NP_651725.1
• Gene: sro / 43512
• FlyBaseID: FBgn0262112
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_932335.1
• Gene: rdh1 / 378440
• ZFINID: ZDB-GENE-030912-15
• Length: 327
• Species: Danio rerio
• Alignment Length: 317
• Identity: 91/317 - (28%)
• Similarity: 147/317 - (46%)
• Gaps: 52/317 - (16%)

  Fly    24 DSRHV-------VLITGCDSGLGHSMAVYCHESLHMTVISCCHNIKSEGAKLLQGLASAKDGLSR 81
            |||.:       |||||||||.|:.:|........:.:..|   :...||..|:..||     .|
Zfish    30 DSRQISGIHEKHVLITGCDSGFGNLVARQLDRQGFLVIAVC---LTETGASKLRATAS-----PR 86

  Fly    82 MHTLELDLLEPDSIRLVHRQLRDILAKDPSYRLTALINNAGV-MCFGEFEWQLTEQIEAQINCNL 145
            :.||:|::.:..||   .|.|..:..:.....|..|:||||| :..|..:|......:..::.||
Zfish    87 LKTLQLNVTDSTSI---DRALEYVRRETGGKGLWGLVNNAGVSVPIGPMDWMQLHDFKKVLDVNL 148

  Fly   146 LGTMRLTHELLPLLRQQQGRIINVTSHCGLQALPALGPYAASKAALRFWTDSLRVELQQYGMEVV 210
            .|.:.:|.:.||||::.|||::||.|..|..::.. |.|..||..:..::||||.::..:|::|.
Zfish   149 TGVIAVTLKFLPLLKKAQGRVVNVASMLGRLSIIG-GGYCLSKFGVEAFSDSLRRDMVHFGVKVS 212

  Fly   211 NFIPGSF--------VLDSNIAARQQQHAQKMREAFSAEQHALYDTYFEAFNGYLKVLSGFKPPN 267
            ...||.|        :::.::..|.....:::|..:.       |:|.:.   |||| ..|.  .
Zfish   213 IIEPGFFKTQVTDLGLIEDDLKKRWSNLPEQVRRDYG-------DSYLQE---YLKV-QEFS--M 264

  Fly   268 RLRNESLLAKFKDALTSSQPLALYIEEPR-RYRL-----YRWL-FTLCPTPLVDWLT 317
            |:...|.|:|    ::|....||....|| ||..     :.|: .:..||.:||..|
Zfish   265 RMLASSDLSK----VSSCMRHALSARHPRTRYAAGWDAKFLWIPLSYLPTCVVDIFT 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sro	NP_651725.1	17beta-HSD-like_SDR_c	27..300	CDD:187632	82/289 (28%)
rdh1	NP_932335.1	Rossmann-fold NAD(P)(+)-binding proteins	40..316	CDD:473865	87/304 (29%)