Protein Alignment sro and Wwox

DIOPT Version :10

• Sequence 1: NP_651725.1
• Gene: sro / 43512
• FlyBaseID: FBgn0262112
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_609171.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Alignment Length: 285
• Identity: 71/285 - (24%)
• Similarity: 106/285 - (37%)
• Gaps: 60/285 - (21%)

  Fly    30 LITGCDSGLGHSMA-VYCHESLHMTVISCCHNIKSEGA---KLLQGLASAKDGLSRMHTLELDLL 90
            ||||.:.|:|:..| ...|....  :|..|.|..|..|   ::.|...:|:   ||.....|||
  Fly   125 LITGANCGIGYETARSLAHHGCE--IIFACRNRSSAEAAIERIAQERPAAR---SRCRFAALDL- 183

  Fly    91 EPDSIRLVHRQLRDILAKDPSYRLTALINNAGVMCFGEFEWQLTEQIEAQINCNLLGTMRLTHEL 155
              .|:|.|.|.:.:|  |.....:..||.||||  |.....:..:.:|.....:.|....||.:|
  Fly   184 --SSLRSVQRFVEEI--KQSVSHIDYLILNAGV--FALPYTRTVDGLETTFQVSHLSHFYLTLQL 242

  Fly   156 LPLLRQQQGRIINVTSHCGLQA-LPA--LGPYAASKAALRFWT---------------DSLRVEL 202
            ..|. ..:.|||.::|.....| ||.  |..:..|....::|:               ..|....
  Fly   243 ETLF-DYKTRIIVLSSESHRFANLPVENLAVHHLSPPPEKYWSMMAYNNAKLCNVLFAQELAQRW 306

  Fly   203 QQYGMEVVNFIPGSFV---LDSN--------------IAARQQQHAQKMREAFSAEQHALYDTYF 250
            :|.|:.|.:..||:.|   |..|              ..:.||..|..:..|.:.|...|...||
  Fly   307 KQRGISVFSLHPGNMVSSDLSRNYWFYRLLFAIVRPFTKSLQQAAATSIYCATANELTGLSGLYF 371

  Fly   251 EAFNGYLKVLSGFKPPNRLRNESLL 275
            .  |.:      |..|::|...:.|
  Fly   372 N--NCF------FCEPSKLSKSAAL 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sro	NP_651725.1	17beta-HSD-like_SDR_c	27..300	CDD:187632	71/285 (25%)
Wwox	NP_609171.1	WW	13..43	CDD:197736
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	71/285 (25%)