DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sro and Mfe2

DIOPT Version :9

Sequence 1:	NP_651725.1	Gene:	sro / 43512	FlyBaseID:	FBgn0262112	Length:	335	Species:	Drosophila melanogaster
Sequence 2:	NP_001285318.1	Gene:	Mfe2 / 32582	FlyBaseID:	FBgn0030731	Length:	598	Species:	Drosophila melanogaster

Alignment Length:	206	Identity:	45/206 - (21%)
Similarity:	80/206 - (38%)	Gaps:	52/206 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 QLKVDSRHVVLITGCDSGLGHSMAVYCHESLHMTVISCCHNIKSEGAKL----LQGLASAKDGLS 80
            :|:.|.| |.::||..:|||...|:...|               .|||:    |.|..|......
  Fly     7 KLRYDGR-VAVVTGAGAGLGREYALLFAE---------------RGAKVVVNDLGGTHSGDGASQ 55

  Fly    81 RMHTLELDLLEP-------------DSIRLVHRQLRDILAKDPSYRLTALINNAGVM------CF 126
            |...:.:|.:..             |..:::...::..      .|:..|:||||::      ..
  Fly    56 RAADIVVDEIRKAGGEAVADYNSVIDGAKVIETAIKAF------GRVDILVNNAGILRDRSLVKT 114

  Fly   127 GEFEWQLTEQIEAQINCNLLGTMRLTHELLPLLRQQQ-GRIINVTSHCGLQALPALGPYAASKAA 190
            .|.:|.|...:      :|.|:.:.|....|.:::|. ||||..:|:.|:........|.|:|..
  Fly   115 SEQDWNLVNDV------HLKGSFKCTQAAFPYMKKQNYGRIIMTSSNSGIYGNFGQVNYTAAKMG 173

  Fly   191 LRFWTDSLRVE 201
            |....:::.:|
  Fly   174 LIGLANTVAIE 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sro	NP_651725.1	17beta-HSD-like_SDR_c	27..300	CDD:187632	42/199 (21%)
sro	NP_651725.1	adh_short	28..229	CDD:278532	42/198 (21%)
Mfe2	NP_001285318.1	hydroxyacyl-CoA-like_DH_SDR_c-like	8..257	CDD:187611	45/205 (22%)
		PRK07791	11..248	CDD:236099	44/202 (22%)
		PLN02864	315..598	CDD:178455
		hot_dog	<383..442	CDD:294345
		HDE_HSD	471..592	CDD:239532
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447503
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930