Protein Alignment sro and rdh8a

DIOPT Version :10

• Sequence 1: NP_651725.1
• Gene: sro / 43512
• FlyBaseID: FBgn0262112
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_957001.1
• Gene: rdh8a / 280648
• ZFINID: ZDB-GENE-021115-3
• Length: 318
• Species: Danio rerio
• Alignment Length: 304
• Identity: 80/304 - (26%)
• Similarity: 133/304 - (43%)
• Gaps: 62/304 - (20%)

  Fly    28 VVLITGCDSGLGHSMAVYC--HESLHMTVISCCHNIKSEGAKLLQGLASAKDGLSRMHTLELDLL 90
            |||||||.||:|..:||..  .|.....||:...::|.:. :|::  |:.:.....:..|.||:.
Zfish     9 VVLITGCSSGIGLRIAVLLARDEQKRYHVIATMRDLKKKD-RLVE--AAGEVYGQTLTLLPLDIC 70

  Fly    91 EPDSIRLVHRQLRDILAKDPSYRLTALINNAGVMCFGEFEWQLTEQIEAQINCNLLGTMRLTHEL 155
            ..:|:|.....::|       ..:..|||||||...|..|....::::.....|..||:|:..|:
Zfish    71 SDESVRQCVNSVKD-------RHIDVLINNAGVGLLGPVESISMDEMKRVFETNFFGTVRMIKEV 128

  Fly   156 LP-LLRQQQGRIINVTSHCGLQALPALGPYAASKAALRFWTDSLRVELQQYGMEVVNFIPGSFVL 219
            :| :.::|.|.||.::|..|||.:.....|.|||.|:..:.:|:.|:|.::.:::....||.  :
Zfish   129 MPDMKKRQAGHIIIMSSVMGLQGVVFNDVYTASKFAIEGFCESMAVQLLKFNVKLSLIEPGP--V 191

  Fly   220 DSNIAARQQQHAQKMREAFSAEQHALY--DTY-------FEAFNGYLKVLSGFKPPNRLRNESLL 275
            .:....:..:...||....:......|  |.|       |||.        |..|.:       :
Zfish   192 HTEFETKMMEEVAKMEYPGADPDTVRYFKDVYVPSSIDIFEAM--------GQTPDD-------I 241

  Fly   276 AK-FKDALTSSQPLALYIEEPRRYR-----LYRWLFTLCPTPLV 313
            || .|..:.:|||         |:|     ||        ||:|
Zfish   242 AKCTKKVIETSQP---------RFRNLTNSLY--------TPIV 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sro	NP_651725.1	17beta-HSD-like_SDR_c	27..300	CDD:187632	75/289 (26%)
rdh8a	NP_957001.1	type1_17beta-HSD-like_SDR_c	8..265	CDD:187666	77/299 (26%)