Protein Alignment sro and Hsd17b6

DIOPT Version :10

• Sequence 1: NP_651725.1
• Gene: sro / 43512
• FlyBaseID: FBgn0262112
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_038814.1
• Gene: Hsd17b6 / 27400
• MGIID: 1351670
• Length: 317
• Species: Mus musculus
• Alignment Length: 305
• Identity: 90/305 - (29%)
• Similarity: 140/305 - (45%)
• Gaps: 48/305 - (15%)

  Fly    29 VLITGCDSGLGHSMAVYCHESLHMTVISCCHNIKSEGAKLLQGLASAKDGLSRMHTLELDLLEPD 93
            |.|||||||.|:.:|... :...|.|::.|  :..:||:.|:...|     .|:.|:.||:.:.:
Mouse    32 VFITGCDSGFGNLLARQL-DRRGMRVLAAC--LTEKGAEELRNKTS-----DRLETVILDVTKTE 88

  Fly    94 SIRLVHRQLRDILAKDPSYRLTALINNAGVM-CFGEFEWQLTEQIEAQINCNLLGTMRLTHELLP 157
            ||....:.:::.:.   ...|..|:|||||: .|...||...|........||:|..::|..:|.
Mouse    89 SIVAATQWVKERVG---DRGLWGLVNNAGVLQPFAYIEWYRPEDYMPIFQVNLIGLTQVTISMLF 150

  Fly   158 LLRQQQGRIINVTSHCGLQALPALGPYAASKAALRFWTDSLRVELQQYGMEVVNFIPGSFVLDSN 222
            |:::.:|||:||:|..|..||.. |.|:.||..:..::|.||.|:|.:|::|....||||..:..
Mouse   151 LVKKARGRIVNVSSALGRVALFG-GFYSCSKYGVEAFSDVLRHEVQDFGVKVSIIEPGSFKTEMT 214

  Fly   223 IAARQQQHAQKMREAFSAEQH-------ALYDTYFEAFNGYLKVLSGFKPPNRLRNESLLAK-FK 279
            .|....:..:|:.||  |.:|       ..:|.:.......|...|        ||.||:.. .:
Mouse   215 DAELTIERTKKVWEA--APEHIKESYGQQFFDDFCSTTKRELMKCS--------RNLSLVTDCME 269

  Fly   280 DALTSSQPLALYIEE--------PRRYRLYRWLFTLCPTPLVDWL 316
            .||||:.|...|...        |..|         .|..|||:|
Mouse   270 HALTSTHPRTRYSAGWDAKFFFIPLSY---------LPASLVDYL 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sro	NP_651725.1	17beta-HSD-like_SDR_c	27..300	CDD:187632	85/287 (30%)
Hsd17b6	NP_038814.1	Rossmann-fold NAD(P)(+)-binding proteins	30..306	CDD:473865	90/305 (30%)