Protein Alignment sro and Rdh8

DIOPT Version :10

• Sequence 1: NP_651725.1
• Gene: sro / 43512
• FlyBaseID: FBgn0262112
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_001025461.1
• Gene: Rdh8 / 235033
• MGIID: 2685028
• Length: 317
• Species: Mus musculus
• Alignment Length: 309
• Identity: 81/309 - (26%)
• Similarity: 133/309 - (43%)
• Gaps: 55/309 - (17%)

  Fly    26 RHVVLITGCDSGLGHSMAV-YCHE-SLHMTVISCCHNI-KSEGAKLLQGLASAKDGLSRMHTLEL 87
            :..|||:||.||:|..:|: ..|: .....|::...:: |.|..:...|.|..|    .:..::|
Mouse     5 QRTVLISGCSSGIGLELALQLAHDPRQRYQVVATMRDLGKKEPLEAAAGEALGK----TLSVVQL 65

  Fly    88 DLLEPDSIRLVHRQLRDILAKDPSYRLTALINNAGVMCFGEFEWQLTEQIEAQINCNLLGTMRLT 152
            |:...:|:       .|.|:.....::..|:|||||...|..|......:::..|.|..|.:||.
Mouse    66 DVCNDESV-------TDCLSHIEGGQVDVLVNNAGVGLVGPLEGLSLATMQSVFNTNFFGAVRLV 123

  Fly   153 HELLP-LLRQQQGRIINVTSHCGLQALPALGPYAASKAALRFWTDSLRVELQQYGMEVVNFIPGS 216
            ..:|| :.|::||.|:.|:|..|||.:.....|||||.||..:.:||.::|:|:.:.:....||.
Mouse   124 KAVLPGMKRRRQGHIVVVSSVMGLQGVMFNDVYAASKFALEGFFESLAIQLRQFNIFISMVEPGP 188

  Fly   217 FVLDSNIAARQQQHAQKMREAFSAEQHALYDT------YF---------EAFNG----------- 255
            ...|.        ..:.:.:...||   ..||      ||         |.|..
Mouse   189 VTTDF--------EGKLLAQVSKAE---FPDTDPDTLGYFRDLYLPASRELFRSVGQSPRDVAQV 242

  Fly   256 YLKVLSGFKPPNRLRNESLLAKFKDALTSSQPL-ALYIEEPRRYRLYRW 303
            ..||:...:||.|.:..:..... .||.:..|. :||::...|. |:||
Mouse   243 IAKVIGTTRPPLRRQTNTRYLPL-TALKAMDPSGSLYVKTAHRL-LFRW 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sro	NP_651725.1	17beta-HSD-like_SDR_c	27..300	CDD:187632	78/303 (26%)
Rdh8	NP_001025461.1	Rossmann-fold NAD(P)(+)-binding proteins	6..263	CDD:473865	72/278 (26%)