Protein Alignment sro and drd-5

DIOPT Version :10

• Sequence 1: NP_651725.1
• Gene: sro / 43512
• FlyBaseID: FBgn0262112
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_509415.2
• Gene: drd-5 / 186315
• WormBaseID: WBGene00018885
• Length: 331
• Species: Caenorhabditis elegans
• Alignment Length: 332
• Identity: 73/332 - (21%)
• Similarity: 135/332 - (40%)
• Gaps: 68/332 - (20%)

  Fly    22 KVDS--RHVVLITGCDSGLGHSMAVYCHESLHMTVISCCHNIKSEGAKLLQGLASAKDGLSRMHT 84
            :||:  :..|.|:|||||.|..:||               .:..:|..::.|:...::|.|....
 Worm    30 RVDNYGKKTVAISGCDSGFGRLLAV---------------RLVKQGVPVIAGVLKKENGESLKKE 79

  Fly    85 LE---------LDLLEPDSIRLVHRQLRDILAKDPSYR-LTALINNAGVM-CFGEFEWQLTEQIE 138
            :.         |::...:|:    ::...::.|....| |..::.|||:: ..|..:|...:...
 Worm    80 VNTPSLLTFGILNVANDESV----KEFVKLVEKTVENRGLWGVVANAGILGNSGPDDWLSAQDYI 140

  Fly   139 AQINCNLLGTMRLTHELLPLLRQQQGRIINVTSHCGLQALPALGPYAASKAALRFWTDSLRVELQ 203
            ..:..|..|.||....|...:::|:||::.::|..|....|.:|||..||.|:..:.|.:|.||.
 Worm   141 NTMQVNTFGVMRFIQGLKKFVKKQEGRVVIISSISGRTPRPTVGPYCVSKHAVEAYADVIRHELI 205

  Fly   204 QYGMEVVNFIPGSFVLD------SNIAARQQQHAQKMREAFSAEQHALYDTYFEA-FNGYLKVLS 261
            .:.:.|....||.|..:      :::.|..::...:.::.:..|   .||.|..: |:.......
 Worm   206 DFNVSVHLLEPGFFTTNITQTATNDLDAVWERLDDETKKEYGKE---FYDDYKNSRFSRLSHCAD 267

  Fly   262 GFKPPNRLRNESLLAKFK--------DALTSSQPLALYIEEPRRYRLYRWLFTLCPTPLVDW-LT 317
            ...|.....:.:||.|:.        |.:....|||                || ||...|| ::
 Worm   268 DLNPVIDAYDHALLGKYPKTRYWVGWDTILFYIPLA----------------TL-PTFAQDWFIS 315

  Fly   318 VRFCAMP 324
            .:.|:.|
 Worm   316 FQRCSRP 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sro	NP_651725.1	17beta-HSD-like_SDR_c	27..300	CDD:187632	63/298 (21%)
drd-5	NP_509415.2	Rossmann-fold NAD(P)(+)-binding proteins	37..314	CDD:473865	69/315 (22%)