Protein Alignment sro and dhs-2

DIOPT Version :10

• Sequence 1: NP_651725.1
• Gene: sro / 43512
• FlyBaseID: FBgn0262112
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_491575.1
• Gene: dhs-2 / 172183
• WormBaseID: WBGene00000966
• Length: 368
• Species: Caenorhabditis elegans
• Alignment Length: 336
• Identity: 92/336 - (27%)
• Similarity: 151/336 - (44%)
• Gaps: 70/336 - (20%)

  Fly    16 LGR---QQLKVD--SRHVVLITGCDSGLGHSMAVYCHESLHMTVISCCHNIKSEGAKLLQGLASA 75
            :||   ::|:::  |:..|.|||||||.|..:|:.|.|. .|.|.:.|  :..:|.:.|.  |.|
 Worm    54 IGRHFIEKLQINNLSKRAVFITGCDSGFGRGLALKCLEQ-GMPVFAGC--LTEQGIESLS--AEA 113

  Fly    76 KDGLSRMHTLELDLLEPDSIRLVHRQLRDILAKDPSY-RLTALINNAGVM---CFGEFEWQLTEQ 136
            :..:....:|:..|::..|...|....:.:..|...| .|.|::||||:.   ...:| ..:.|.
 Worm   114 RKSIGNGRSLDAFLMDVTSDESVGEVAKRLEKKCEQYGGLHAVVNNAGITGKHIADDF-LDINEY 177

  Fly   137 IEAQINCNLLGTMRLTHELLPLLRQQQGRIINVTSHCGLQALPALGPYAASKAALRFWTDSLRVE 201
            ::. .|.||.|.:|.|..:..||::.:||::.|.|.|....||.||||:.||..:..:.|.:|.|
 Worm   178 LKV-ANINLWGPIRTTMAVKKLLKKARGRVVTVASICARVGLPGLGPYSVSKYGVSAYCDVIRQE 241

  Fly   202 LQQYGMEVVNFIPGSFVLDSNIAARQQQHAQKMREAFSAEQHALYDTYFEAFNGYLKVLSGFKPP 266
            |:.:|:.|....||.|  ::.:..|::..|    |...|.:||                     |
 Worm   242 LRPFGISVHVLEPGFF--NTPLINREKIDA----EILEAWKHA---------------------P 279

  Fly   267 NRLRNESLLAKFKDALTS---------SQPLALYIE---------EPR-RYRLYRW-------LF 305
            |.::.|.....|.||..|         |..::|.::         .|| ||:: .|       .|
 Worm   280 NEVKQEYGEKFFNDARESTHLFLNSVASSQISLVVDAYFHAITSKHPRSRYQI-GWDSILLFIPF 343

  Fly   306 TLCPTPLVDWL 316
            :..||.|.|::
 Worm   344 SYLPTGLQDYI 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sro	NP_651725.1	17beta-HSD-like_SDR_c	27..300	CDD:187632	82/295 (28%)
dhs-2	NP_491575.1	Rossmann-fold NAD(P)(+)-binding proteins	70..354	CDD:473865	88/318 (28%)