Protein Alignment sro and SDR9C7

DIOPT Version :10

• Sequence 1: NP_651725.1
• Gene: sro / 43512
• FlyBaseID: FBgn0262112
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_683695.1
• Gene: SDR9C7 / 121214
• HGNCID: 29958
• Length: 313
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 94/306 - (30%)
• Similarity: 153/306 - (50%)
• Gaps: 26/306 - (8%)

  Fly    25 SRHVVLITGCDSGLGHSMAVYCHESLHMTVISCCHNIKSEGAKLLQGLASAKDGLSRMHTLELDL 89
            |...|.|||||||.|:.:|....:. .|.|::.|  ...||::.||     :|...|:.|..||:
Human    24 SEKYVFITGCDSGFGNLLAKQLVDR-GMQVLAAC--FTEEGSQKLQ-----RDTSYRLQTTLLDV 80

  Fly    90 LEPDSIRLVHRQLRDILAKDPSYRLTALINNAGV-MCFGEFEWQLTEQIEAQINCNLLGTMRLTH 153
            .:.:||:...:.:||   |.....|.||:||||| :..|..||...:.....||.||:|.:.:|.
Human    81 TKSESIKAAAQWVRD---KVGEQGLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIEVTL 142

  Fly   154 ELLPLLRQQQGRIINVTSHCGLQALPALGPYAASKAALRFWTDSLRVELQQYGMEVVNFIPGSF- 217
            .:||::::.:||::|::|..|..|:.. |.|..||..:..::||:|.||..:|::|....||::
Human   143 HMLPMVKRARGRVVNMSSSGGRVAVIG-GGYCVSKFGVEAFSDSIRRELYYFGVKVCIIEPGNYR 206

  Fly   218 --VL-DSNIAARQQQHAQKMREAFSAEQHALY-DTYFEAFNGYLKVLSGFKPPNRLRNESLLAKF 278
              :| ..|:.:|.    :|:.|....|....| :.||..:...||.:.....| |:|:  ::...
Human   207 TAILGKENLESRM----RKLWERLPQETRDSYGEDYFRIYTDKLKNIMQVAEP-RVRD--VINSM 264

  Fly   279 KDALTSSQPLALYIEEPRRYRLYRWLFTLCPTPLVDWLTVRFCAMP 324
            :.|:.|..|...|........||..|..| |||:.|::..|:...|
Human   265 EHAIVSRSPRIRYNPGLDAKLLYIPLAKL-PTPVTDFILSRYLPRP 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sro	NP_651725.1	17beta-HSD-like_SDR_c	27..300	CDD:187632	83/278 (30%)
SDR9C7	NP_683695.1	type2_17beta_HSD-like_SDR_c	26..302	CDD:187665	91/295 (31%)