Protein Alignment sro and DHRS9

DIOPT Version :10

• Sequence 1: NP_651725.1
• Gene: sro / 43512
• FlyBaseID: FBgn0262112
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: NP_001276692.1
• Gene: DHRS9 / 10170
• HGNCID: 16888
• Length: 379
• Species: Homo sapiens
• Alignment Length: 308
• Identity: 87/308 - (28%)
• Similarity: 149/308 - (48%)
• Gaps: 28/308 - (9%)

  Fly    20 QLKVD--SRHVVLITGCDSGLGHSMA-VYCHESLHMTVISCCHNIKSEGAKLLQGLASAKDGLSR 81
            :||::  :...:.|||||||.|:..| .:..:..|  ||:.|  :...|:..|:...|     .|
Human    81 KLKIEDITDKYIFITGCDSGFGNLAARTFDKKGFH--VIAAC--LTESGSTALKAETS-----ER 136

  Fly    82 MHTLELDLLEPDSIRLVHRQLRDILAKDPSYRLTALINNAGVM-CFGEFEWQLTEQIEAQINCNL 145
            :.|:.||:.:|::::...:.:::.:.:.   .|..|||||||. .....:|...|.....|..||
Human   137 LRTVLLDVTDPENVKRTAQWVKNQVGEK---GLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNL 198

  Fly   146 LGTMRLTHELLPLLRQQQGRIINVTSHCGLQALPALGPYAASKAALRFWTDSLRVELQQYGMEVV 210
            .|.:.:|..:|||:::.|||:|||:|..|..|:.. |.|..||.|:..:.||||.:::.:|:.|.
Human   199 FGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVS 262

  Fly   211 NFIPGSFVLDSNIAARQQQHAQKMR--EAFSAEQHALY-DTYFEAFNGYLKVLSGFKPPNRLRNE 272
            ...||.|  .:|:|...:...:|:.  |..|.:....| :.|.|.   .|..|.|.|....:...
Human   263 CIEPGLF--KTNLADPVKVIEKKLAIWEQLSPDIKQQYGEGYIEK---SLDKLKGNKSYVNMDLS 322

  Fly   273 SLLAKFKDALTSSQPLALYIEEPRRYRLYRWL-FTLCPTPLVDWLTVR 319
            .::.....||||..|...| ...:..::: |: .:..|..|.|:|.::
Human   323 PVVECMDHALTSLFPKTHY-AAGKDAKIF-WIPLSHMPAALQDFLLLK 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sro	NP_651725.1	17beta-HSD-like_SDR_c	27..300	CDD:187632	80/277 (29%)
DHRS9	NP_001276692.1	type2_17beta_HSD-like_SDR_c	90..366	CDD:187665	84/295 (28%)