Protein Alignment sro and hsd11b2

DIOPT Version :10

• Sequence 1: NP_651725.1
• Gene: sro / 43512
• FlyBaseID: FBgn0262112
• Length: 335
• Species: Drosophila melanogaster
• Sequence 2: XP_002937366.1
• Gene: hsd11b2 / 100489854
• XenbaseID: XB-GENE-1012826
• Length: 388
• Species: Xenopus tropicalis
• Alignment Length: 296
• Identity: 92/296 - (31%)
• Similarity: 142/296 - (47%)
• Gaps: 34/296 - (11%)

  Fly    18 RQQLKVDSRHVVLITGCDSGLGHSMAVYCHESLHMTVISCCHNIKSEGAKLLQGLASAKDGLSRM 82
            ::.|.|:.: ||.|||||||.| ::|.:..:|:...||:...|::|.||:.|:.:.|  |.|:
 Frog    79 KRTLPVEGK-VVFITGCDSGFG-NVAAHKLDSMGFKVIATVLNLESPGARKLRKICS--DNLT-- 137

  Fly    83 HTLELDLLEPDSIRLVHRQLRDILAKDPSYRLTALINNAGVMC-FGEFEWQLTEQIEAQINCNLL 146
             .:::||.:.:.|:...:..:   .......|.|||||||... ||:.|..|....:|.::.|..
 Frog   138 -IIQMDLTKQEDIQKAQQTTK---LHTAGRGLWALINNAGYCAHFGDAELTLMSTYKACMDVNFF 198

  Fly   147 GTMRLTHELLPLLRQQQGRIINVTSHCGLQALPALGPYAASKAALRFWTDSLRVELQQYGMEVVN 211
            ||:.||..|||.:|..:|||:.|.|..|..:.|.|..|.:|||||....|..|.||..:|::|:.
 Frog   199 GTLELTQALLPFIRYAKGRIVTVGSPAGEHSFPYLAAYGSSKAALNRVMDIFRHELMPWGVKVIL 263

  Fly   212 FIPGSFVLDS--NIAARQQQHAQKMREAFSAEQHALYDTYFEAF-----NGYLK----VLSGFKP 265
            .:|.|:...:  |....:.|| :|:......|   |...|.|.:     |.:||    ..|.|.|
 Frog   264 ILPASYKTGAHDNHIHWENQH-KKLLANLPIE---LLQEYGEEYITETQNRFLKYGDTACSDFSP 324

  Fly   266 PNRLRNESLLAKFKDALTSSQPLALYIEEPRRYRLY 301
                    ::....||:.|..|...|......:.||
 Frog   325 --------VIDSITDAIISENPKVKYYAGKNLWILY 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sro	NP_651725.1	17beta-HSD-like_SDR_c	27..300	CDD:187632	88/284 (31%)
hsd11b2	XP_002937366.1	type2_17beta_HSD-like_SDR_c	87..367	CDD:187665	90/288 (31%)