DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ATPsyngamma and ATP3

DIOPT Version :9

Sequence 1:	NP_524550.1	Gene:	ATPsyngamma / 43507	FlyBaseID:	FBgn0020235	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_009595.1	Gene:	ATP3 / 852327	SGDID:	S000000243	Length:	311	Species:	Saccharomyces cerevisiae

Alignment Length:	303	Identity:	113/303 - (37%)
Similarity:	190/303 - (62%)	Gaps:	21/303 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 AMEATMLAQQQRGM----------ATLKMISIRLKSVKNIQKITQSMKMVSAAKYARAERDLKAA 67
            |..:.|..|.|.|:          ||||.:.:||||:|||:|||::||:|::.:.::||:...:|
Yeast    10 ATRSVMCHQAQVGILYKTNPVRTYATLKEVEMRLKSIKNIEKITKTMKIVASTRLSKAEKAKISA 74

  Fly    68 RPYGIGAQQFFEKTE-----IQPDEKAEPKKLLIAVTSDRGLCGAVHTGVARLIRGELAQDEANT 127
            :......|.|::..|     ::..|...||:|::|:|||:||||::|:.:|:.:|..| .|:.|.
Yeast    75 KKMDEAEQLFYKNAETKNLDVEATETGAPKELIVAITSDKGLCGSIHSQLAKAVRRHL-NDQPNA 138

  Fly   128 KVFCVGDKSRAILSRLYGKNILMVANEVGRLPPTFLDASKIANE---VLQTGYDYTEGKIVYNRF 189
            .:..:|||.:..|.|.:..||.:..|.:|:..|||.:::.||::   |::.| .|.:..|.||..
Yeast   139 DIVTIGDKIKMQLLRTHPNNIKLSINGIGKDAPTFQESALIADKLLSVMKAG-TYPKISIFYNDP 202

  Fly   190 KSVVSYQCSTLPIFSGSTVEKSEKLAVYD-SLDSDVVKSYLEFSLASLIFYTMKEGACSEQSSRM 253
            .|.:|::.|..|||:..|:|:|.....:: ..|::|.:...|::||:.:...|.:|..:|.|:|.
Yeast   203 VSSLSFEPSEKPIFNAKTIEQSPSFGKFEIDTDANVPRDLFEYTLANQMLTAMAQGYAAEISARR 267

  Fly   254 TAMDNASKNAGEMIDKLTLTFNRTRQAVITRELIEIISGAAAL 296
            .||||||||||:||::.::.:|||||||||.||::||:||::|
Yeast   268 NAMDNASKNAGDMINRYSILYNRTRQAVITNELVDIITGASSL 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATPsyngamma	NP_524550.1	F1-ATPase_gamma	27..293	CDD:213394	105/274 (38%)
ATP3	NP_009595.1	ATPsyn_F1gamma	34..310	CDD:273469	107/277 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345765
Domainoid	1	1.000	197	1.000	Domainoid score	I586
eggNOG	1	0.900	-	-		E1_COG0224
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3792
Inparanoid	1	1.050	199	1.000	Inparanoid score	I860
Isobase	1	0.950	-	0	Normalized mean entropy	S748
OMA	1	1.010	-	-		QHG54014
OrthoFinder	1	1.000	-	-		FOG0004011
OrthoInspector	1	1.000	-	-		oto99635
orthoMCL	1	0.900	-	-		OOG6_100847
Panther	1	1.100	-	-	LDO	PTHR11693
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R120
SonicParanoid	1	1.000	-	-		X3294
TreeFam	1	0.960	-	-
	16	15.740