DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ATPsyngamma and Atp5c1

DIOPT Version :9

Sequence 1:	NP_524550.1	Gene:	ATPsyngamma / 43507	FlyBaseID:	FBgn0020235	Length:	297	Species:	Drosophila melanogaster
Sequence 2:	NP_065640.2	Gene:	Atp5c1 / 11949	MGIID:	1261437	Length:	298	Species:	Mus musculus

Alignment Length:	279	Identity:	163/279 - (58%)
Similarity:	217/279 - (77%)	Gaps:	6/279 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 QQRGMATLKMISIRLKSVKNIQKITQSMKMVSAAKYARAERDLKAARPYGIGAQQFFEKTEIQ-P 85
            |.|.|||||.|:.||||:|||||||:|||||:|||||||||:||.||.||.|:...:||.:|: |
Mouse    21 QVRNMATLKDITRRLKSIKNIQKITKSMKMVAAAKYARAERELKPARVYGTGSLALYEKADIKAP 85

  Fly    86 DEKAEPKKLLIAVTSDRGLCGAVHTGVARLIRGELAQDEANTK---VFCVGDKSRAILSRLYGKN 147
            ::|  .|.|:|.|:||||||||:|:.||:.::.|:|...|..|   :..||:|.:.||.|.:...
Mouse    86 EDK--KKHLIIGVSSDRGLCGAIHSSVAKQMKNEVAALTAAGKEVMIVGVGEKIKGILYRTHSDQ 148

  Fly   148 ILMVANEVGRLPPTFLDASKIANEVLQTGYDYTEGKIVYNRFKSVVSYQCSTLPIFSGSTVEKSE 212
            .|:...:|||.||||.|||.||.|:|.:||::.||.|::|:||||:||:....||||.:|:..:|
Mouse   149 FLVSFKDVGRKPPTFGDASVIALELLNSGYEFDEGSIIFNQFKSVISYKTEEKPIFSLNTIATAE 213

  Fly   213 KLAVYDSLDSDVVKSYLEFSLASLIFYTMKEGACSEQSSRMTAMDNASKNAGEMIDKLTLTFNRT 277
            .:::||.:|:||:::|.|::||:||:|::||...||||:||||||||||||.:||||||||||||
Mouse   214 TMSIYDDIDADVLQNYQEYNLANLIYYSLKESTTSEQSARMTAMDNASKNASDMIDKLTLTFNRT 278

  Fly   278 RQAVITRELIEIISGAAAL 296
            ||||||:||||||||||||
Mouse   279 RQAVITKELIEIISGAAAL 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATPsyngamma	NP_524550.1	F1-ATPase_gamma	27..293	CDD:213394	155/269 (58%)
Atp5c1	NP_065640.2	ATPsyn_F1gamma	26..297	CDD:273469	158/272 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848005
Domainoid	1	1.000	301	1.000	Domainoid score	I1407
eggNOG	1	0.900	-	-		E1_COG0224
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3792
Inparanoid	1	1.050	307	1.000	Inparanoid score	I2598
Isobase	1	0.950	-	0	Normalized mean entropy	S748
OMA	1	1.010	-	-		QHG54014
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004011
OrthoInspector	1	1.000	-	-		oto93591
orthoMCL	1	0.900	-	-		OOG6_100847
Panther	1	1.100	-	-	LDO	PTHR11693
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R120
SonicParanoid	1	1.000	-	-		X3294
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.740