Protein Alignment IntS11 and Ints11

DIOPT Version :9

• Sequence 1: NP_651721.1
• Gene: IntS11 / 43506
• FlyBaseID: FBgn0039691
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_082296.1
• Gene: Ints11 / 71957
• MGIID: 1919207
• Length: 600
• Species: Mus musculus
• Alignment Length: 595
• Identity: 409/595 - (68%)
• Similarity: 487/595 - (81%)
• Gaps: 2/595 - (0%)

  Fly     1 MPDIKITPLGAGQDVGRSCLLLSMGGKNIMLDCGMHMGYNDERRFPDFSYIVPEGPITSHIDCVI 65
            ||:|::|||||||||||||:|:|:.|||:||||||||||||:|||||||||...|.:|..:||||
Mouse     1 MPEIRVTPLGAGQDVGRSCILVSISGKNVMLDCGMHMGYNDDRRFPDFSYITQSGRLTDFLDCVI 65

  Fly    66 ISHFHLDHCGALPYMSEIVGYTGPIYMTHPTKAIAPILLEDMRKVAVERKGESNFFTTQMIKDCM 130
            ||||||||||||||.||:|||.|||||||||:||.||||||.||:||::|||:||||:|||||||
Mouse    66 ISHFHLDHCGALPYFSEMVGYDGPIYMTHPTQAICPILLEDYRKIAVDKKGEANFFTSQMIKDCM 130

  Fly   131 KKVIPVTLHQSMMVDTDLEIKAYYAGHVLGAAMFWIKVGSQSVVYTGDYNMTPDRHLGAAWIDKC 195
            |||:.|.|||::.||.:|||||||||||||||||.|||||:||||||||||||||||||||||||
Mouse   131 KKVVAVHLHQTVQVDDELEIKAYYAGHVLGAAMFQIKVGSESVVYTGDYNMTPDRHLGAAWIDKC 195

  Fly   196 RPDLLISESTYATTIRDSKRCRERDFLKKVHECVAKGGKVLIPVFALGRAQELCILLETYWERMN 260
            ||:|||:|||||||||||||||||||||||||.|.:|||||||||||||||||||||||:|||||
Mouse   196 RPNLLITESTYATTIRDSKRCRERDFLKKVHETVERGGKVLIPVFALGRAQELCILLETFWERMN 260

  Fly   261 LKYPIYFALGLTEKANTYYKMFITWTNQKIRKTFVHRNMFDFKHIKPFDKAYIDNPGAMVVFATP 325
            ||.||||:.|||||||.|||:||||||||||||||.||||:|||||.||:.:.||||.|||||||
Mouse   261 LKVPIYFSTGLTEKANHYYKLFITWTNQKIRKTFVQRNMFEFKHIKAFDRTFADNPGPMVVFATP 325

  Fly   326 GMLHAGLSLQIFKKWAPNENNMVIMPGYCVQGTVGNKILGGAKKVEFENRQVVEVKMAVEYMSFS 390
            ||||||.|||||:|||.||.|||||||||||||||:|||.|.:|:|.|.||::||||.|||||||
Mouse   326 GMLHAGQSLQIFRKWAGNEKNMVIMPGYCVQGTVGHKILSGQRKLEMEGRQMLEVKMQVEYMSFS 390

  Fly   391 AHADAKGIMQLIQNCEPKNVMLVHGEAGKMKFLRSKIKDEFNLETYMPANGETCVISTPVKIPVD 455
            |||||||||||:...||::|:||||||.||:|||.||:.||.:..||||||||..:.|...|||.
Mouse   391 AHADAKGIMQLVGQAEPESVLLVHGEAKKMEFLRQKIEQEFRVSCYMPANGETVTLPTSPSIPVG 455

  Fly   456 ASVSLLKAEARSYNAQPPDPKRRRLIHGVLVMKDNRIMLQNLTDALKEIGINRHVMRFTSKVKMD 520
            .|:.|||.|  ......|:.|:.||:||.|:|||:...|.:...||||:|:..|.:|||.:|.:.
Mouse   456 ISLGLLKRE--MVQGLLPEAKKPRLLHGTLIMKDSNFRLVSSEQALKELGLAEHQLRFTCRVHLQ 518

  Fly   521 DSGPVIRTSERLKTLLEEKLAGWTVTMQENGSIAIESVEVKVEEDEKDPKQKNILISWTNQDEDI 585
            |:.....|:.|:.:.|:..|....|....:||:.:||:.::.....:||..|.:|:|||.|||::
Mouse   519 DTRKEQETALRVYSHLKSTLKDHCVQHLPDGSVTVESILIQAAAHSEDPGTKVLLVSWTYQDEEL 583

  Fly   586 GAYILNVLQN 595
            |:::..:|:|
Mouse   584 GSFLTTLLKN 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IntS11	NP_651721.1	YSH1	4..446	CDD:224157	354/441 (80%)
		INTS11-like_MBL-fold	6..204	CDD:293849	159/197 (81%)
		Beta-Casp	245..363	CDD:214983	98/117 (84%)
		RMMBL	376..416	CDD:284853	29/39 (74%)
Ints11	NP_082296.1	YSH1	4..444	CDD:224157	353/439 (80%)
		INTS11-like_MBL-fold	6..204	CDD:293849	159/197 (81%)
		HXHXDH motif	68..73		4/4 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850167
Domainoid	1	1.000	305	1.000	Domainoid score	I1361
eggNOG	1	0.900	-	-		E1_COG1236
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9894
Inparanoid	1	1.050	852	1.000	Inparanoid score	I432
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53735
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006201
OrthoInspector	1	1.000	-	-		oto94731
orthoMCL	1	0.900	-	-		OOG6_102863
Panther	1	1.100	-	-	LDO	PTHR11203
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4389
SonicParanoid	1	1.000	-	-		X4481
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790