Protein Alignment IntS11 and Dclre1a

DIOPT Version :10

• Sequence 1: NP_651721.1
• Gene: IntS11 / 43506
• FlyBaseID: FBgn0039691
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: XP_006527280.1
• Gene: Dclre1a / 55947
• MGIID: 1930042
• Length: 1047
• Species: Mus musculus
• Alignment Length: 405
• Identity: 76/405 - (18%)
• Similarity: 137/405 - (33%)
• Gaps: 117/405 - (28%)

  Fly    10 GAGQDVGRSC-LLLSMGGKNIMLDCGMHMGYNDERRFPDFSYIVPEGPITSHIDCV--IISHFHL 71
            ||| :|.|:| ....:.|....:|.              |.|...||       |.  .::|||.
Mouse   700 GAG-EVRRTCPFYKRIPGTGFTVDA--------------FQYGEIEG-------CTAYFLTHFHS 742

  Fly    72 DHCGALPYMSEIVGYTGPIYMTHPTKAIAPILLEDMRKVAVERKGESNFFTTQMIKDCMKKVIPV 136
            ||     |......:|.|:|.:.    |...||:  :|:.|:   |.......|..:|:...:.|
Mouse   743 DH-----YAGLSKDFTRPVYCSE----ITGNLLK--KKLRVQ---EQYIRQLPMDTECVVDSVKV 793

  Fly   137 TLHQSMMVDTDLEIKAYYAGHVLGAAMFWIKVGSQSVV-YTGDYNMTPD--------RHLGAAWI 192
            .|     :|         |.|..||.|...::.:.:|: :|||:...|.        |.:...::
Mouse   794 VL-----LD---------ANHCPGATMILFQLPNGAVILHTGDFRADPSMERSRLAGRKVHTLFL 844

  Fly   193 DK--CRPDLLISESTYATTIRDSKRCRERDFLKKVHECVAKGGKVLI--PVFALGRAQELCILLE 253
            |.  |.|:.............          :....|.|....:.|:  ..:.:|:.:....:.:
Mouse   845 DTTYCSPEYTFPSQQEVIQFA----------INTAFEAVTLNPRALVVCGTYCIGKEKVFLAIAD 899

  Fly   254 TYWERMNL---KYPIYFALGLTEKANTYYKMFITWTNQKIRKTFVH---RNMFDFK----HIKPF 308
            ....::.:   ||.....|.:.|.::     .||   ..:..:.||   ....:||    |:|..
Mouse   900 VLGSKVGMSQEKYKTLQCLNIPEVSS-----LIT---TDMCDSLVHLLPMMQINFKGLQSHLKKC 956

  Fly   309 DKAYIDNPGAMVVFATPGMLHAGLSLQIFKKWAPNENNMVIMPGYCVQGTVGNKILGGAKKVEF- 372
            ...|    ..::.|...|..|               :|.:......:..|.||..:.|   :.:
Mouse   957 GGKY----DQILAFRPTGWTH---------------SNNITSTADIIPQTRGNISIYG---IPYS 999

  Fly   373 ENRQVVEVKMAVEYM 387
            |:...:|:|..|:::
Mouse  1000 EHSSYLEMKRFVQWL 1014

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IntS11	NP_651721.1	YSH1	5..416	CDD:440849	76/405 (19%)
		INTS11-like_MBL-fold	6..204	CDD:293849	47/207 (23%)
Dclre1a	XP_006527280.1	metallo-hydrolase-like_MBL-fold	696..851	CDD:451500	46/200 (23%)
		DRMBL	921..1027	CDD:429512	22/124 (18%)