Protein Alignment IntS11 and Cpsf73

DIOPT Version :9

• Sequence 1: NP_651721.1
• Gene: IntS11 / 43506
• FlyBaseID: FBgn0039691
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_650738.1
• Gene: Cpsf73 / 42240
• FlyBaseID: FBgn0261065
• Length: 684
• Species: Drosophila melanogaster
• Alignment Length: 610
• Identity: 211/610 - (34%)
• Similarity: 320/610 - (52%)
• Gaps: 79/610 - (12%)

  Fly     1 MPD-----IKITPLGAGQDVGRSCLLLSMGGKNIMLDCGMHMGYNDERRFPDFSYIVPEGPITSH 60
            |||     ::|.||||||:|||||::|...||.||||||:|.|.:.....|....|..:     .
  Fly    10 MPDEESDLLQIKPLGAGQEVGRSCIMLEFKGKKIMLDCGIHPGLSGMDALPYVDLIEAD-----E 69

  Fly    61 IDCVIISHFHLDHCGALPYMSEIVGYTGPIYMTHPTKAIAPILLEDMRKVAVERKGESNFFTTQM 125
            ||.:.|||||||||||||:......:.|..:|||.||||...:|.|..|:       ||..|.||
  Fly    70 IDLLFISHFHLDHCGALPWFLMKTSFKGRCFMTHATKAIYRWMLSDYIKI-------SNISTEQM 127

  Fly   126 ------IKDCMKKVIPVTLHQSMMVDTDLEIKAYYAGHVLGAAMFWIKVGSQSVVYTGDYNMTPD 184
                  ::..|:|:..:..|:...| ..:...||.||||||||||.|::....::||||::...|
  Fly   128 LYTEADLEASMEKIETINFHEERDV-MGVRFCAYIAGHVLGAAMFMIEIAGIKILYTGDFSRQED 191

  Fly   185 RHLGAAWIDKCRPDLLISESTYATTIRDSKRCRERDFLKKVHECVAKGGKVLIPVFALGRAQELC 249
            |||.||.:...:||:||:||||.|.|.:.:..||..|...|.:.|.:||:.|||||||||||||.
  Fly   192 RHLMAAEVPPMKPDVLITESTYGTHIHEKREDRENRFTSLVQKIVQQGGRCLIPVFALGRAQELL 256

  Fly   250 ILLETYW-ERMNL-KYPIYFALGLTEKANTYYKMFITWTNQKIRKTFVHRNMFDFKHI---KPFD 309
            ::|:.:| :..:| :.|||:|..|.:|....|:.:|...|.:||:.....|.|.|:||   |..|
  Fly   257 LILDEFWSQNPDLHEIPIYYASSLAKKCMAVYQTYINAMNDRIRRQIAVNNPFVFRHISNLKGID 321

  Fly   310 KAYIDNPGAMVVFATPGMLHAGLSLQIFKKWAPNENNMVIMPGYCVQGTVGNKILGGAKKVEFEN 374
              :.::.|..|:.|:|||:.:|||.::|:.|..:..|.||:.||||:||:...:|...:::...:
  Fly   322 --HFEDIGPCVIMASPGMMQSGLSRELFESWCTDPKNGVIIAGYCVEGTLAKAVLSEPEEITTLS 384

  Fly   375 RQVVEVKMAVEYMSFSAHADAKGIMQLIQNCEPKNVMLVHGEAGKMKFLRSKIKDEF------NL 433
            .|.:.:.|:|:|:|||||.|.:...:.|:..:|.:|:|||||..:|..|:..::.|:      ::
  Fly   385 GQKLPLNMSVDYISFSAHTDYQQTSEFIRLLKPTHVVLVHGEQNEMSRLKLALQREYEADASTDI 449

  Fly   434 ETYMPAN---------GETCVISTPVKIPVDASVSLLKAEARSYNAQPPDPKRRRLIHGVLVMKD 489
            :.|.|.|         ||...       .|..|::...:|..|            .:.||||.:|
  Fly   450 KFYNPRNTHAVDLYFRGEKTA-------KVMGSLAAKNSEVGS------------KLSGVLVKRD 495

  Fly   490 NRIMLQNLTDALKEIGINRHVMRFTSKVKMDDSGPVIRTSERLKTLLEEKLAGWTVTMQENGSIA 554
            .:..|...:|      :.::.....|.|....|.|...:...|:.||:...||....::....:.
  Fly   496 FKYHLLAPSD------LGKYTDMSMSVVTQRQSIPWGSSLSTLELLLDRIGAGCVEVLEAERKLR 554

  Fly   555 I-ESVEVKVEEDEKDPKQKNILISW 578
            : ..:|:.||       ||.|::.|
  Fly   555 VFGCIELTVE-------QKIIVMEW 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IntS11	NP_651721.1	YSH1	4..446	CDD:224157	181/467 (39%)
		INTS11-like_MBL-fold	6..204	CDD:293849	87/203 (43%)
		Beta-Casp	245..363	CDD:214983	45/122 (37%)
		RMMBL	376..416	CDD:284853	16/39 (41%)
Cpsf73	NP_650738.1	YSH1	18..456	CDD:224157	178/452 (39%)
		CPSF3-like_MBL-fold	18..211	CDD:293850	87/205 (42%)
		Beta-Casp	252..373	CDD:214983	45/122 (37%)
		RMMBL	386..426	CDD:284853	16/39 (41%)
		CPSF73-100_C	483..683	CDD:215023	24/115 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440178
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1236
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D210835at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11203
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850