Protein Alignment IntS11 and ysh1

DIOPT Version :9

• Sequence 1: NP_651721.1
• Gene: IntS11 / 43506
• FlyBaseID: FBgn0039691
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_594263.2
• Gene: ysh1 / 2542258
• PomBaseID: SPAC17G6.16c
• Length: 757
• Species: Schizosaccharomyces pombe
• Alignment Length: 642
• Identity: 200/642 - (31%)
• Similarity: 319/642 - (49%)
• Gaps: 82/642 - (12%)

  Fly     9 LGAGQDVGRSCLLLSMGGKNIMLDCGMHMGYNDERRFPDFSYIVPEGPITSHIDCVIISHFHLDH 73
            ||||.:|||||.::...||.:|||.|:|..|......|.|...     ..|.:|.::||||||||
pombe    24 LGAGNEVGRSCHVIQYKGKTVMLDAGVHPAYTGLSALPFFDEF-----DLSTVDVLLISHFHLDH 83

  Fly    74 CGALPYMSEIVGYTGPIYMTHPTKAIAPILLEDMRKVAVERKG-ESNFFTTQMIKDCMKKVIPVT 137
            ..:|||:.:...:.|.::|||||||:...||.|.  |.|...| |...:..:.:.....::..|.
pombe    84 VASLPYVMQKTNFRGRVFMTHPTKAVCKWLLSDY--VKVSNVGMEDQLYDEKDLLAAFDRIEAVD 146

  Fly   138 LHQSMMVDTDLEIKAYYAGHVLGAAMFWIKVGSQSVVYTGDYNMTPDRHLGAAWIDKCRPDLLIS 202
            .|.::.|: .::...|:|||||||.|:::::...::::||||:...||||..|.:...|||:||:
pombe   147 YHSTIEVE-GIKFTPYHAGHVLGACMYFVEMAGVNILFTGDYSREEDRHLHVAEVPPKRPDVLIT 210

  Fly   203 ESTYATTIRDSKRCRERDFLKKVHECVAKGGKVLIPVFALGRAQELCILLETYW-ERMNLK-YPI 265
            ||||.|.....:..:|...|..:|..:..||:||:|||||||||||.::|:.|| ..::|: .||
pombe   211 ESTYGTASHQPRLEKEARLLNIIHSTIRNGGRVLMPVFALGRAQELLLILDEYWNNHLDLRSVPI 275

  Fly   266 YFALGLTEKANTYYKMFITWTNQKIRKTFVHRNMFDFKHIKPF-DKAYIDNPGAMVVFATPGMLH 329
            |:|..|..|....::.::...|..|||.|..||.|.|:.:|.. :....|:.|..|:.|:||||.
pombe   276 YYASSLARKCMAIFQTYVNMMNDNIRKIFAERNPFIFRFVKSLRNLEKFDDIGPSVILASPGMLQ 340

  Fly   330 AGLSLQIFKKWAPNENNMVIMPGYCVQGTVGNKILGGAKKVEFENRQVVEVKMAVEYMSFSAHAD 394
            .|:|..:.::|||:..|.:::.||.|:||:..:|.....::...:.|.:..:||||.:||:||.|
pombe   341 NGVSRTLLERWAPDPRNTLLLTGYSVEGTMAKQITNEPIEIVSLSGQKIPRRMAVEELSFAAHVD 405

  Fly   395 AKGIMQLIQNCEPKNVMLVHGEAGKMKFLRSKIKDEF-----NLETYMPANGETCVISTPVKIPV 454
            .....:.|......:::|||||...|..|:|.:..:|     :::.|.|.|   ||   |:.:|.
pombe   406 YLQNSEFIDLVNADHIILVHGEQTNMGRLKSALASKFHNRKVDVKVYTPRN---CV---PLYLPF 464

  Fly   455 DASVSLLKAEARSYNAQPPDPKRRRLIHGVLVMKD--NRIM----LQNLTDALKEIGINRHVMRF 513
            ... .|::|..:   .....||...::.|:|:.||  .::|    |::.:|....:...:.|:.|
pombe   465 KGE-RLVRALGK---VAVHKPKEGDIMSGILIQKDANYKLMSAEDLRDFSDLTTTVLTQKQVIPF 525

  Fly   514 -------------------TSKVKMDDSGPVIRTSERLKTLLEEKLA-GWTVTMQENGSIA---- 554
                               .||.|.......:..:..|..:.|.||| .|...:. |.:||
pombe   526 FSSMELANFHLKQMFGYVKQSKTKAGQPQYTVMDAITLTLIQEHKLALEWVGNIM-NDTIADSVI 589

  Fly   555 -----IES--VEVKVEED---------EKDPKQKNILISWTNQDEDIGAYILNVLQN 595
                 |||  ..||:...         :|.||        .:::||....::..|.|
pombe   590 TILLGIESSPASVKLTSHKCNHLHSHLDKPPK--------VSKEEDRIKKLMMFLDN 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IntS11	NP_651721.1	YSH1	4..446	CDD:224157	160/445 (36%)
		INTS11-like_MBL-fold	6..204	CDD:293849	73/195 (37%)
		Beta-Casp	245..363	CDD:214983	43/120 (36%)
		RMMBL	376..416	CDD:284853	14/39 (36%)
ysh1	NP_594263.2	YSH1	19..462	CDD:224157	162/451 (36%)
		CPSF3-like_MBL-fold	19..212	CDD:293850	73/195 (37%)
		Beta-Casp	253..374	CDD:214983	43/120 (36%)
		RMMBL	387..427	CDD:284853	14/39 (36%)
		CPSF73-100_C	484..650	CDD:288554	33/164 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1236
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53735
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820