Protein Alignment IntS11 and cpsf-3

DIOPT Version :9

• Sequence 1: NP_651721.1
• Gene: IntS11 / 43506
• FlyBaseID: FBgn0039691
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_502553.2
• Gene: cpsf-3 / 178285
• WormBaseID: WBGene00013460
• Length: 707
• Species: Caenorhabditis elegans
• Alignment Length: 588
• Identity: 198/588 - (33%)
• Similarity: 301/588 - (51%)
• Gaps: 85/588 - (14%)

  Fly     7 TPLGAGQDVGRSCLLLSMGGKNIMLDCGMHMGYN--DERRFPDFSYIVPEGPITSHIDCVIISHF 69
            ||||:||:|||||.||...||.:|||||:|.|.:  |...|.||..|       .:||.::|:||
 Worm    14 TPLGSGQEVGRSCHLLEYKGKRVMLDCGVHPGLHGVDALPFVDFVEI-------ENIDLLLITHF 71

  Fly    70 HLDHCGALPYMSEIVGYTGPIYMTHPTKAIAPILLEDMRKVAVERKG---ESNFFTTQMIKDCMK 131
            |||||||||::.:...:.|..:|||.||||..:||.|.  |.:.:.|   .:..:|...::..|.
 Worm    72 HLDHCGALPWLLQKTAFQGKCFMTHATKAIYRMLLGDY--VRISKYGGPDRNQLYTEDDLEKSMA 134

  Fly   132 KVIPVTLHQSMMVDTDLEIKAYYAGHVLGAAMFWIKVGSQSVVYTGDYNMTPDRHLGAAWIDKCR 196
            |:..:...:...|: .:....|.|||||||..|.|::....|:||||::...||||.||.|....
 Worm   135 KIETIDFREQKEVN-GIRFWPYVAGHVLGACQFMIEIAGVRVLYTGDFSCLEDRHLCAAEIPPIT 198

  Fly   197 PDLLISESTYATTIRDSKRCRERDFLKKVHECVAKGGKVLIPVFALGRAQELCILLETYWERMNL 261
            |.:||:||||.|...:.:..||:.|.:.||:.|.:||:.|||.||:|.||||.::|:.|||....
 Worm   199 PQVLITESTYGTQTHEDRAVREKRFTQMVHDIVTRGGRCLIPAFAIGPAQELMLILDEYWESHQE 263

  Fly   262 KY--PIYFALGLTEKANTYYKMFITWTNQKIRKTFVHRNMFDFKHI---KPFDKAYIDNPGAMVV 321
            .:  |:|:|..|.:|..:.|:.|:...|.:|:|....:|.|.|||:   :..|:  .::.|..||
 Worm   264 LHDIPVYYASSLAKKCMSVYQTFVNGMNSRIQKQIAVKNPFIFKHVSTLRGMDQ--FEDAGPCVV 326

  Fly   322 FATPGMLHAGLSLQIFKKWAPNENNMVIMPGYCVQGTVGNKILGGAKKVEFENRQVVEVKMAVEY 386
            .||||||.:|.|.::|:.|.|:..|..|:.||||:||:...||...:::...:.:.:.::|.|.|
 Worm   327 LATPGMLQSGFSRELFESWCPDTKNGCIIAGYCVEGTLAKHILSEPEEIVSLSGEKLPMRMQVGY 391

  Fly   387 MSFSAHADAKGIMQLIQNCEPKNVMLVHGEAGKMKFLRSKIKDEF-------------------- 431
            :|||||.|.......::..:|.:::|||||..:|..|:|.|:.:|
 Worm   392 VSFSAHTDYHQTSNFVKALKPPHLVLVHGELHEMSRLKSGIERQFQDDNIPIEVHNPRNTERLQL 456

  Fly   432 ------------NLETYMPANGETCVISTPVKIPVDASVSLLKAEARSYNAQPPDPKRRR----- 479
                        .|...:|.|.|| :....||.....|: ::..|..||.:.......:|
 Worm   457 QFRGEKTAKVIGKLAQRVPENNET-ISGVLVKNNFSYSI-MVPEELGSYTSLRISSLEQRMSVHY 519

  Fly   480 ------LIHGVLVMKDNRIMLQNLTDALKEI----GINRHVMRFTSKVKMD------------DS 522
                  ||..:..:.|:..::||:  .||||    .:.:.:..|..||.:.            ||
 Worm   520 SGSLKLLIFNLQQLNDDACLIQNI--KLKEISKKGSVTQAITVFQGKVNVTVYGNDHVVVVRWDS 582

  Fly   523 GPV 525
            .||
 Worm   583 NPV 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IntS11	NP_651721.1	YSH1	4..446	CDD:224157	175/480 (36%)
		INTS11-like_MBL-fold	6..204	CDD:293849	83/201 (41%)
		Beta-Casp	245..363	CDD:214983	46/122 (38%)
		RMMBL	376..416	CDD:284853	13/39 (33%)
cpsf-3	NP_502553.2	CPSF3-like_MBL-fold	11..206	CDD:293850	83/201 (41%)
		YSH1	13..456	CDD:224157	170/453 (38%)
		Beta-Casp	247..368	CDD:214983	46/122 (38%)
		RMMBL	381..421	CDD:284853	13/39 (33%)
		CPSF73-100_C	477..694	CDD:215023	26/113 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1236
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53735
OrthoDB	1	1.010	-	-		D210835at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.830