Protein Alignment IntS11 and Cpsf73

DIOPT Version :10

• Sequence 1: NP_651721.1
• Gene: IntS11 / 43506
• FlyBaseID: FBgn0039691
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: XP_321933.6
• Gene: Cpsf73 / 1281946
• VectorBaseID: AGAMI1_008254
• Length: 690
• Species: Anopheles gambiae
• Alignment Length: 576
• Identity: 215/576 - (37%)
• Similarity: 311/576 - (53%)
• Gaps: 54/576 - (9%)

  Fly     6 ITPLGAGQDVGRSCLLLSMGGKNIMLDCGMHMGYNDERRFPDFSYIVPEGPITSHIDCVIISHFH 70
            |.||||||:|||||::|...||.||||||:|.|.:.....|....|..:     .||.:.|||||
Mosquito    22 IRPLGAGQEVGRSCIMLEFKGKKIMLDCGIHPGLSGMDALPFVDLIDAD-----QIDLLFISHFH 81

  Fly    71 LDHCGALPYMSEIVGYTGPIYMTHPTKAIAPILLEDMRKVAVERKGESNFFTTQM------IKDC 129
            ||||||||:..:...:.|..:|||.||||...:|.|..||       ||..|.||      ::..
Mosquito    82 LDHCGALPWFLQKTSFKGRCFMTHATKAIYRWMLSDYIKV-------SNISTDQMLYTEADLEAS 139

  Fly   130 MKKVIPVTLHQSMMVDTDLEIKAYYAGHVLGAAMFWIKVGSQSVVYTGDYNMTPDRHLGAAWIDK 194
            |:|:..:..|:...: ..:...||.||||||||||.|::....|:||||::...||||.||.|..
Mosquito   140 MEKIETINFHEERDI-LGVRFWAYNAGHVLGAAMFMIEIAGIRVLYTGDFSRQEDRHLMAAEIPA 203

  Fly   195 CRPDLLISESTYATTIRDSKRCRERDFLKKVHECVAKGGKVLIPVFALGRAQELCILLETYW-ER 258
            .|||:||:||||.|.|.:.:..||..|...|.:.|.:||:.|||||||||||||.::|:.|| :.
Mosquito   204 MRPDVLITESTYGTHIHEKREDRENRFTSLVQKIVQQGGRCLIPVFALGRAQELLLILDEYWSQN 268

  Fly   259 MNL-KYPIYFALGLTEKANTYYKMFITWTNQKIRKTFVHRNMFDFK---HIKPFDKAYIDNPGAM 319
            .:| :.|||:|..|.:|....|:.:|...|.|||:.....|.|.|:   ::|..|  :.|:.|..
Mosquito   269 PDLQEIPIYYASSLAKKCMAVYQTYINAMNDKIRRQIAINNPFVFRFISNLKGID--HFDDVGPC 331

  Fly   320 VVFATPGMLHAGLSLQIFKKWAPNENNMVIMPGYCVQGTVGNKILGGAKKVEFENRQVVEVKMAV 384
            ||.|:|||:.:|||.::|:.|..:..|.||:.||||:||:...||...:::...|.|.:.:.|:|
Mosquito   332 VVMASPGMMQSGLSRELFESWCTDPKNGVIIAGYCVEGTLAKTILFEPEEITSMNGQKLPLNMSV 396

  Fly   385 EYMSFSAHADAKGIMQLIQNCEPKNVMLVHGEAGKMKFLRSKIKDEF------NLETYMPANGET 443
            :|:|||||.|.:...:.|:..:|.:|:|||||..:|..|:|.:..|:      .:..:.|.|
Mosquito   397 DYISFSAHTDYQQTSEFIRLLQPTHVVLVHGEQNEMGRLKSALMREYEANPKVQITFHNPRN--- 458

  Fly   444 CVISTPVKIPVDASVSLLKAEARSYNAQPPDPKRRRLIHGVLVMKDNRIMLQNLTDALKEIGINR 508
               :.||::..... ...|........:|.|.:|   :.||||.::.:..|...||..|...::.
Mosquito   459 ---TQPVELYFRGE-KTAKVMGTLAVGEPADCQR---LSGVLVKREFKYHLLAPTDLSKYTDMSM 516

  Fly   509 HVMRFTSKVKMDDSGPVIRTSERLKTLLEEKLAGWTVTMQE----NGSIAIESVEV 560
            .::  |.|..:...|..:    .||.|||.  ||...::.|    .||.|...:.|
Mosquito   517 SIV--TQKQSIHWPGSTV----VLKLLLER--AGGPGSVVETPIPEGSTATARLRV 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IntS11	NP_651721.1	YSH1	5..416	CDD:440849	178/420 (42%)
		INTS11-like_MBL-fold	6..204	CDD:293849	90/203 (44%)
Cpsf73	XP_321933.6	None