DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CIA30 and Ndufaf1

DIOPT Version :9

Sequence 1:	NP_651718.1	Gene:	CIA30 / 43503	FlyBaseID:	FBgn0039689	Length:	296	Species:	Drosophila melanogaster
Sequence 2:	NP_001099970.1	Gene:	Ndufaf1 / 296086	RGDID:	1306202	Length:	328	Species:	Rattus norvegicus

Alignment Length:	321	Identity:	103/321 - (32%)
Similarity:	170/321 - (52%)	Gaps:	54/321 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LPAVQQQIHTTAVHRTFW--------------------EREKKSGYKTKLPEPSKKQMIMDGLRD 59
            :.::.:.:..|.:||.|.                    ..:|:.....|:.:..|.:..:.| .|
  Rat     1 MASIHKLLIGTYIHRNFLRPRAAVPPFVGNHFVDYSSSSLQKQVASANKVSQQGKTEEGLQG-HD 64

  Fly    60 LKEEM---------------KLWRQEVKEQFE--SDPILVFRPG------------ETDVVFDFK 95
            .||..               |..|.|..|.|.  .|.|:....|            :..||:.|:
  Rat    65 HKEVALDVPSPDRTPEVSFDKAIRDEAMEHFRRLKDEIVAHVRGPDGRPLHEVIMEQARVVWQFR 129

  Fly    96 APDVLDKWTVTTDADHGEGKSTATLELSAAG-AGLFHGQVNSDHTKDGIIKRTGYANIRTKRVRK 159
            ..:.||||.:|:|...| |:|...|::|... :.|.:|.::|:..:||...::||..:.::..|.
  Rat   130 EKEDLDKWILTSDKTIG-GRSEIFLKMSKNNRSALLYGTLSSEAPQDGESNQSGYCAMISRIPRG 193

  Fly   160 SFKRETTYDWTQYNMLVMKVRGDGRSYLINLHTEGYFDLMWNDIYHYVLYTRGGPHWQIAKIPFS 224
            :|:|:.:|||:|:|.|.::||||||.:::|:..:..|....|.:|.|.::|||||:||..|||||
  Rat   194 AFERKLSYDWSQFNTLYLRVRGDGRPWMVNIKQDTEFIQRKNQMYSYFMFTRGGPYWQEVKIPFS 258

  Fly   225 KFFLSSKGRVQDRQGAIPLNRVTHFGFSVAAKKGMDGPFGLEIDYVGLEYDPSHREEFAYE 285
            |||.|::||::|.||.:.|::::..||:::.|  :||||.||||::|:..||:|.||||||
  Rat   259 KFFFSNQGRIRDVQGPLILDKISSIGFTLSDK--VDGPFFLEIDFIGVFTDPAHTEEFAYE 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CIA30	NP_651718.1	CIA30	92..267	CDD:285718	69/175 (39%)
Ndufaf1	NP_001099970.1	CIA30	126..299	CDD:400728	69/175 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353484
Domainoid	1	1.000	146	1.000	Domainoid score	I4447
eggNOG	1	0.900	-	-		E1_KOG2435
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32289
Inparanoid	1	1.050	175	1.000	Inparanoid score	I3974
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1563319at2759
OrthoFinder	1	1.000	-	-		FOG0007033
OrthoInspector	1	1.000	-	-		oto97082
orthoMCL	1	0.900	-	-		OOG6_103519
Panther	1	1.100	-	-	LDO	PTHR13194
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5127
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.760