DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kul and Adam26a

DIOPT Version :10

Sequence 1:NP_651716.1 Gene:Kul / 43501 FlyBaseID:FBgn0039688 Length:1537 Species:Drosophila melanogaster
Sequence 2:NP_001162590.1 Gene:Adam26a / 290763 RGDID:1559501 Length:710 Species:Rattus norvegicus


Alignment Length:345 Identity:97/345 - (28%)
Similarity:142/345 - (41%) Gaps:93/345 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   570 YDAFCLAYMFTYRDFEMGTLGLAWTGDLKNAGGVCEKNGHYRGSLKSLNTGIVTLLNYGKHVPPA 634
            ||   :.::|...|::| .||||      |...||..:.      .::|:.|.::::....:   
  Rat   294 YD---IIHLFVRHDYDM-YLGLA------NVATVCTPDN------CAVNSFISSVMSDMAFI--- 339

  Fly   635 VSHVTLAHEIGHNFGSPHDPEQCTPGGEDGNFIMFARATSGDKKNNNKFSTCSLKSIEPVLNAKA 699
                 :|||:|||.|..||...||.|.||.....:       |.|:.|||.||.:.:..|:..: 
  Rat   340 -----VAHEMGHNLGMKHDVNGCTCGLEDCIMAPY-------KSNSPKFSNCSHEEMYSVVTQR- 391

  Fly   700 RSMKGCFTEPQS-----SICGNGVVEPGEQCDCGWEEDC-KDSCCFPMSRQPRLDETPCTLTPHA 758
               |..:..|::     ::|||.:||.|||||||..|.| ||.||          ...|.|.|.|
  Rat   392 ---KCLYNTPEALVTNLTMCGNKLVEKGEQCDCGNLESCLKDPCC----------SKDCVLKPGA 443

  Fly   759 RCSPSQGPCCTTDCKLKFGDKCR-DDNGCRDPSFCDGRVPQCPPSVNKPNKTICNKEFVCYMGDC 822
            :|  :.|.||.....|:.|..|| :.|.|..|.:|:|..|:||..|.|.:...|:.:..||...|
  Rat   444 QC--AFGLCCKNCQFLQTGTVCRKEKNECDLPEWCNGTSPECPRDVYKEDGNPCSGDGYCYKMAC 506

  Fly   823 TGSICLAYGLESCQCIPGPQDDRIKSCELCCKLPGEDSPCRSSFEWNEAPFDVPDMYSKPGTPCN 887
                              .|.|     |.|.|:.|..|.......:.|        .:|.|    
  Rat   507 ------------------HQHD-----EQCRKIFGNGSRSAGEICYTE--------MNKRG---- 536

  Fly   888 DYNGYC----DVFQKCREVD 903
            |..|.|    ..:::|:..|
  Rat   537 DRFGNCGNDSSKYRRCKRAD 556

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KulNP_651716.1 Pep_M12B_propep 70..186 CDD:460254
ZnMc_TACE_like 479..713 CDD:239798 38/147 (26%)
Disintegrin 720..801 CDD:459709 33/82 (40%)
Adam26aNP_001162590.1 Pep_M12B_propep 42..160 CDD:460254
ZnMc_adamalysin_II_like 208..396 CDD:239797 37/136 (27%)
Disintegrin 414..486 CDD:459709 34/83 (41%)
ACR 491..626 CDD:214743 19/101 (19%)
Blue background indicates that the domain is not in the aligned region.

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