Protein Alignment Kul and ADAMDEC1

DIOPT Version :10

• Sequence 1: NP_651716.1
• Gene: Kul / 43501
• FlyBaseID: FBgn0039688
• Length: 1537
• Species: Drosophila melanogaster
• Sequence 2: NP_055294.1
• Gene: ADAMDEC1 / 27299
• HGNCID: 16299
• Length: 470
• Species: Homo sapiens
• Alignment Length: 319
• Identity: 75/319 - (23%)
• Similarity: 111/319 - (34%)
• Gaps: 100/319 - (31%)

  Fly   483 LYLQADHTFFQKMGSDEASIEAITRHVQR-ANTIYRNTDFN---------NDGKPDNITFMIKRI 537
            |||..|:.|::....:...|.:....|.. .|.||...|..         :||         .:|
Human   222 LYLVLDNAFYKNYNENLTLIRSFVFDVMNLLNVIYNTIDVQVALVGMEIWSDG---------DKI 277

  Fly   538 KVHNMNAMKDPSYRFPGNYGVEKFLELFSE------EDYDAFCLAYMFTYRDFEMGTLGLAWTGD 596
            ||     :...|..|      :.||...|.      .|:     |.:.:...|....:|||.:..
Human   278 KV-----VPSASTTF------DNFLRWHSSNLGKKIHDH-----AQLLSGISFNNRRVGLAASNS 326

  Fly   597 LKNAGGVC-----EKNGHYRGSLKSLNTGIVTLLNYGKHVPPAVSHVTLAHEIGHNFGSPHDP-- 654
            |.:...|.     :||          |..:|.:               ::||:||..|.|..|
Human   327 LCSPSSVAVIEAKKKN----------NVALVGV---------------MSHELGHVLGMPDVPFN 366

  Fly   655 EQCTPGGEDGNFIMFARATSGDKKNNNKFST-CS------LKSIEPVLNAKARSMKGCFTEPQSS 712
            .:|    ..|:.:|....:|...|:   ||| |.      |.|.:|....:|.......|.|
Human   367 TKC----PSGSCVMNQYLSSKFPKD---FSTSCRAHFERYLLSQKPKCLLQAPIPTNIMTTP--- 421

  Fly   713 ICGNGVVEPGEQCDCGWEEDCKDSCCFPMSRQPRLDETPCTLTPHARCSPSQGPCCTTD 771
            :|||.::|.||.||||..::|.:.||         :...|.|.|...|. ...|..||:
Human   422 VCGNHLLEVGEDCDCGSPKECTNLCC---------EALTCKLKPGTDCG-GDAPNHTTE 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kul	NP_651716.1	Pep_M12B_propep	70..186	CDD:460254
		ZnMc_TACE_like	479..713	CDD:239798	55/259 (21%)
		Disintegrin	720..801	CDD:459709	17/52 (33%)
ADAMDEC1	NP_055294.1	Pep_M12B_propep	43..171	CDD:460254
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	173..200
		Reprolysin	218..412	CDD:426256	52/246 (21%)
		Disintegrin	429..>461	CDD:471982	13/40 (33%)