Protein Alignment Kul and Tace

DIOPT Version :10

• Sequence 1: NP_651716.1
• Gene: Kul / 43501
• FlyBaseID: FBgn0039688
• Length: 1537
• Species: Drosophila melanogaster
• Sequence 2: XP_312572.6
• Gene: Tace / 1273579
• VectorBaseID: AGAMI1_013847
• Length: 759
• Species: Anopheles gambiae
• Alignment Length: 979
• Identity: 230/979 - (23%)
• Similarity: 352/979 - (35%)
• Gaps: 328/979 - (33%)

  Fly    20 LPGEILAIPTPLK-------LPGYTHRLTPYIKHWEAANFDRQVLQAAQVRHLEQARFRQKREVT 77
            ||..||.:...:.       |.|..|:   .:|::|       .|.|..:.|      |.::..|
Mosquito     3 LPSIILTVVLVVSFAVLIAPLQGQLHK---NLKYYE-------TLHAKDLSH------RIEKRGT 51

  Fly    78 PSASGLAHTIR-LNFSAHDRDFRLVLRQQP---HSVF-AHDVEIENTLGPIDYDVSRIYTGSLED 137
            ..::...:||: :.|....|.|||:|....   ||.| |:.|:...:...:..|.|..:.|.:..
Mosquito    52 KHSNHPFNTIKEVEFKVLGRKFRLILHPHASVLHSNFRAYTVDGNGSESIVHLDRSNFFKGRVFG 116

  Fly   138 DEAAHVQAILTSDNLLDGTIETQAEHYYIEPAHRYSQQLAESGVHSIVYKLSDVNMQKQQFTGGG 202
            :..:||.|.: .|.::..::....|.|:|||:.|:...|::.  |.|.|:.||:.....|.....
Mosquito   117 EMESHVNAHI-DDGVMTASVVLPDETYHIEPSWRHLPHLSDK--HMIAYRTSDIKFSWDQVDAIS 178

  Fly   203 LNSATPAKTHCASEKLRKKRWLPEELAMSDAPAPTYNRNPPLPLDLEVPYNDDFRVLASEEDKSE 267
            .:...|          |...::.|.|.:....                         |.|:::.|
Mosquito   179 GDLGVP----------RTCGYIKEGLELEGQE-------------------------AEEDEEIE 208

  Fly   268 ESPRKYPTTSTTRSTVRSTESFLATLTKPTSNRNILVNNYNPSNLGEGSRSYSSGNNNANSNSNN 332
            ....:|.|.|                 .||
Mosquito   209 GDTERYETDS-----------------DPT----------------------------------- 221

  Fly   333 NNSNNNNNNNNSNNNVRKLYTKHKNIIVSTYNRPIEPEFGTPYEEPNNNGTRELPSNFFNANWTT 397
                                                                  |...::|
Mosquito   222 ------------------------------------------------------PETVWHA---- 228

  Fly   398 LFLGNNNNGNDRPSHKTHVEIITKNGATKKPNIIVNNYNPEIIFAPNPHNPSFNSMMMTNLLSGR 462
                     .|||..|.         :.:|.......|.|
Mosquito   229 ---------EDRPESKR---------SRRKRQADQYEYTP------------------------- 250

  Fly   463 GGEDIHSSPRLLYDRKTTCMLYLQADHTFFQKMG--SDEASIEAITRHVQRANTIYRNTDFNNDG 525
                          .||.|.|.|.||:.|||:||  :.:.:|..:...:.|.:.||.:|.:.:..
Mosquito   251 --------------TKTRCPLLLVADYRFFQEMGGSNTKTTINYLISLIDRVHKIYNDTIWQDRS 301

  Fly   526 KPD---NITFMIKRIKVHNMNAMKDPSYRFPG----------NYGVEKFLELFSEE-DYDAFCLA 576
            ..:   .:.|:||:|.||:     :|: |..|          .:.|...||:||.| .:..||||
Mosquito   302 DQEGFKGMGFVIKKIVVHS-----EPT-RVRGGEAHYNMVREKWDVRNLLEVFSREYSHKDFCLA 360

  Fly   577 YMFTYRDFEMGTLGLAWTGDLK--NAGGVCEKNGHYRGSLKSLNTGIVTLLN-YGKHVPPAVSHV 638
            ::||...||.|.||||:.|..:  :.||:|.......|....||:|:.:..| ||:.|....:.:
Mosquito   361 HLFTDLKFEGGILGLAYVGSPRRNSVGGICTPEYFKNGYTLYLNSGLSSSRNHYGQRVITREADL 425

  Fly   639 TLAHEIGHNFGSPHDPE--QCTP-GGEDGNFIMFARATSGDKKNNNKFSTCSLKSIEPVLNAKAR 700
            ..|||.|||:||.|||:  :|:| ..:.|:|:|:..:.||...||.|||.|||:||..||.||:.
Mosquito   426 VTAHEFGHNWGSEHDPDIPECSPSASQGGSFLMYTYSVSGYDVNNKKFSPCSLRSIRKVLQAKSG 490

  Fly   701 SMKGCFTEPQSSICGNGVVEPGEQCDCG--WEEDCKDSCCFPMSRQPRLDETPCTLTPH--ARCS 761
            .   ||:||:.|.|||..||..||||.|  ..|| .|:||          :..|.|..:  |.||
Mosquito   491 R---CFSEPEESFCGNLRVEGDEQCDAGLLGTED-NDACC----------DKNCKLRRNQGAVCS 541

  Fly   762 PSQGPCCTTDCKLKFGDKCRDDN--GCRDPSFCDGRVPQCPPSVNKPNKTICNKEFVCYMGDCTG 824
            ....|||.....:..|.|||:..  .|...:.|.|...:||.|....:.|:|.:...|..|.|.
Mosquito   542 DKNSPCCQNCQYMMAGVKCREAQYATCEQEARCTGNHAECPKSPPMSDGTMCQERGQCRNGKCV- 605

  Fly   825 SICLAYGLESCQCIPGPQDDRIKSCELCCKLPGEDSPCRSSFEWNEAPFDVPDMYSKPGTPCNDY 889
            ..|...||:||.|     |....:|:.|         ||.|......|.:.||:. ..||||  .
Mosquito   606 PYCETQGLQSCMC-----DIIADACKRC---------CRQSINETCFPVEPPDVL-PDGTPC--I 653

  Fly   890 NGYC----------DVFQKCREVDPSGPLATLRKLLLSEESIASFKKWMQHNWYTVALAAVGVIL 944
            .|:|          ||.::..::             :.|.:|....::::.|      ..:.|::
Mosquito   654 QGFCNKGMCEKTIQDVVERFWDI-------------IEEININKVLRFLRDN------IVMAVVM 699

  Fly   945 LLAL 948
            |.||
Mosquito   700 LTAL 703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kul	NP_651716.1	Pep_M12B_propep	70..186	CDD:460254	31/120 (26%)
		ZnMc_TACE_like	479..713	CDD:239798	92/255 (36%)
		Disintegrin	720..801	CDD:459709	27/86 (31%)
Tace	XP_312572.6	None