Protein Alignment Kul and adam23b

DIOPT Version :10

• Sequence 1: NP_651716.1
• Gene: Kul / 43501
• FlyBaseID: FBgn0039688
• Length: 1537
• Species: Drosophila melanogaster
• Sequence 2: XP_021334457.1
• Gene: adam23b / 101884782
• ZFINID: ZDB-GENE-070810-3
• Length: 760
• Species: Danio rerio
• Alignment Length: 801
• Identity: 175/801 - (21%)
• Similarity: 262/801 - (32%)
• Gaps: 277/801 - (34%)

  Fly   227 ELAMSDAPAPTYNRNPPLPLDLEVPYNDDFRVLASEEDKSEESPRKYPTTSTTRSTV--RSTESF 289
            ||..:|.||.....|...|.|.:...:...|::....:.||.:   |...:|...|.  |:.|:.
Zfish    26 ELLQNDDPASGQQLNSSGPQDTQHTLSYPSRLIYYLHENSEST---YHDLNTHAKTTDPRAQEAH 87

  Fly   290 LAT------------LTKPTSNRNILVNNYNPSNLGE--------GSRSYSSGNNNANSNSNNNN 334
            ||.            :...|.|.::|.::|...:..|        |...|..|......:|....
Zfish    88 LAQTSFQLQAFGSQFILDLTLNNDLLSSDYVEIHYEEEKPVLWKGGEHCYYHGQIRGVEDSRVAL 152

  Fly   335 SNNNNNNNNSNNNVRKLYTKHKNIIVSTYNRPIEPEFGTPYEEPNNNGTRELPSNFFNANWTTLF 399
            |..|..:...::.|. |||             |||        .|...|.|
Zfish   153 STCNGLHGMFDDGVH-LYT-------------IEP--------LNQTHTIE-------------- 181

  Fly   400 LGNNNNGNDRPS--HKTHVEIITKNGATKKPNIIVNNYNPEIIFAPNPHNPSFNSMMMTNLLSGR 462
                  |..|..  |:|.::                            .:||.....|....|..
Zfish   182 ------GTARAHVLHRTDLQ----------------------------QSPSAREEGMEEDFSWL 212

  Fly   463 GGEDIHSSPRLLYDRKTTCMLYLQADHTFFQKMGSDEAS----------IEAI------TRHVQR 511
            ......:.||.:::......|.:..||..|:::.:.:.:          ::||      ||.|..
Zfish   213 RRRKKRAIPRNVFEEMKYIELMIVIDHNMFKRLKTKQHTRNNAKSVVNLVDAIFKEHLNTRVVLV 277

  Fly   512 ANTIYRNTDFNNDGKPDNIT--FMIKRIKVHNMNAMKDPSYRFPGNYGVEKFLELFSEE--DYDA 572
            |..|:  ||  .|..|.::|  .|::....:....::..:          ..::|||..  .|..
Zfish   278 AVEIW--TD--KDRIPVSVTPFEMLRNFSKYRQQHIRQHA----------DTVQLFSNVTFHYPR 328

  Fly   573 FCLAYMFTYRDFEMGTLGLAWTGDLKNAGGVCEKNGHYRGSLKSLNTGIVTLLNYGKHVPPAVS- 636
            ...||.                      ||:|           |.:.| |.::.||.....|:.
Zfish   329 SSAAYF----------------------GGMC-----------SASHG-VGVIEYGTQWTMALQL 359

  Fly   637 HVTLAHEIGHNFGSPHDPEQC-----TPG--GEDGNFIMFARATSGDKKNNNKFSTCSLKSIEPV 694
            ..:||..:|..:.|....:.|     .||  .||.. :...||          ||.||:.|.:..
Zfish   360 SQSLAQNLGIQWDSASKRKDCGCVNSWPGCIMEDTG-VQHPRA----------FSKCSIVSFKEF 413

  Fly   695 LNAKARSMKG---C-FTEP----QSSICGNGVVEPGEQCDCGWEEDCKDSCCFPMSRQPRLDETP 751
            |      :||   | |.:|    :.:.||||.||.||:||||..::|...||           ..
Zfish   414 L------LKGGGSCLFNKPSKLFEDTECGNGYVEVGEECDCGPRDECYKDCC-----------KK 461

  Fly   752 CTLTPHARCSPSQGPCCTTDCKL-KFGDKCR-DDNGCRDPSFCDGRVPQCPPSVNKPNKTICN-K 813
            |:|:..|.|  |.||||...|.. ..|..|| ..|.|.....|.|....|||:::|.:...|: .
Zfish   462 CSLSNGAHC--SDGPCCNNTCLFYSRGHTCRYAVNDCDISETCTGDSGLCPPNLHKQDGYFCSLN 524

  Fly   814 EFVCYMGDC--TGSIC-------------LAY------GLESCQCIPGPQDDRIKSCE------- 850
            :..||.|:|  ..|.|             ..|      |.|...|  ||..|:...|.
Zfish   525 QGRCYAGECKTRDSQCKYVWGPKAASSEKFCYEKLNTEGSEKGNC--GPDGDKWTQCSKHDVFCG 587

  Fly   851 --LCC---KLP------GEDSP-----------CRSSFEWNEAPFDVPDMYSKPGTPCNDYNGYC 893
              ||.   ::|      ||.:|           |..:....:...||.  |.:.||||.. :..|
Zfish   588 FLLCTNTGRIPRIGIIKGEITPTNFNHQGRLIDCSGAHVLLDDQTDVG--YVEDGTPCGP-SMMC 649

  Fly   894 DVFQKCREVD-------PSGP 907
             |.:||..:.       |:||
Zfish   650 -VDRKCLPIQYLNLSSCPNGP 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kul	NP_651716.1	Pep_M12B_propep	70..186	CDD:460254
		ZnMc_TACE_like	479..713	CDD:239798	54/269 (20%)
		Disintegrin	720..801	CDD:459709	28/82 (34%)
adam23b	XP_021334457.1	Pep_M12B_propep	80..189	CDD:460254	27/150 (18%)
		Reprolysin	229..426	CDD:426256	53/261 (20%)
		Disintegrin	441..512	CDD:459709	29/83 (35%)
		ACR	516..657	CDD:214743	33/146 (23%)